The differentiation of cytotoxic T lymphocyte precursor cells (CTL-P) into CTL effector cells is a two-step process. In the first step, naïve CTL-P (CTL-PN) become activated (CTL-PA) but do not yet have the capacity to kill target cells. CTL-PA can be distinguished from CTL-PN because the former are far less sensitive than the latter to the effects of in vitro-generated suppressor cells. Thus, ...

few studies have been conducted on the causative factors associated with the development of cancer. infection by high risk human papillomaviruses (hpvs) have been implicated as causative agents in a variety of cancers. hpv is capable of evading immune system and establishing persistent infections. prolonged infection and lesion maintenance are associated with higher risk of neoplastic progressi...

although the structure of human t lymphoptropic virus type i (htlv-i) has been known well, the function of some proteins encoded by htlv-i px region is not fully understood. furthermore, the responses of the immune system to htlv-i remain still unknown. most of htlv-i-infected individuals show a strong and persistently activated cytotoxic t-cell (ctl) response to the virus. the frequency of htl...

Globally, almost 2 billion cubic meters of industrial roundwood are harvested yearly. Two the most common methods harvest and extraction cut-to-length (CTL) full-tree or tree-length (FT/TL). The aim this study was to compile data on annual volumes by main in forestry countries. To quantify effect potential explanatory variables, were subjected linear regression analysis, using shares fully mech...

Abstract Biomechanics is a fundamental feature of cell. However, the manner by which actomysin tension affects tumor immune evasion remains unclear. Here we show that although cytotoxic T lymphocytes (CTL) can effectively destroy stiff differentiated cells, they fail to kill soft tumor-repopulating cells (TRC). TRC softness prevented membrane pore formation caused CTL-released perforin. Perfori...

This study aimed to determine the effect of implementation Contextual Teaching and Learning (CTL) model with outdoor approach towards students’ ability in mathematical representation. It was quasi-experimental research consisting two experimental classes one control group. used a pretest-posttest group design. The population this students SUPM Tegal. Sampling conducted using cluster random thre...

AbstrakTujuan dari penelitian untuk mengetahui rata-rata hasil belajar matematika siswa yang diperoleh melalui model pembelajaran bamboo dancing menggunakan pendekatan CTL lebih baik pada dancing. Populasi dalam ini adalah seluruh kelas VIII MTs Islamiyah Sukoharjo. Instrumen berupa tes uraian. Analisis data uji-t dengan prasyarat uji normalitas dan homogenitas. Berdasarkan analisis disimpulkan...

The study aims to: 1) develop valid, practical, and effective quality learning materials for class VII SMP Berastagi 1 Program that focuses on the contextual teaching model with Karo cultural context (CTL-KCC); 2) examine enhancement of students' math problem-solving abilities as a side effect using CTL- KCC materials. This research is development 4-D consisting four stages: define, design, dev...

Two subsets of human CTL have been defined based upon phenotype and function: CD4(-) CD8(-) double-negative (DN) CTL lyse susceptible targets via Fas-Fas ligand interaction and CD8(+) CTL via the granule exocytosis pathway. CD8(+) CTL, but not DN CTL, can mediate an antimicrobial activity against Mycobacterium tuberculosis-infected target cells that is dependent on cytotoxic granules that conta...