BACKGROUND Photodynamic therapy with a self-adhesive 5-aminolaevulinic acid (5-ALA) patch shows high efficacy rates in the treatment of mild to moderate actinic keratosis (AK) in short term trials. OBJECTIVES The purpose of the trial was to follow up patients after successful 5-ALA patch-PDT at 3 month intervals over a total period of 12 months. Patients who had received placebo-PDT or cryosu...

Introduction: The Study Aimed To Compare The Results of Cryosurgery With Trichloroacetic Acid Chemical (TCA) Cautery For The Treatment of Hypertrophied Nasal Turbinates.   Materials and Methods: This was a prospective study of 70 patients with nasal obstruction due to hypertrophied nasal turbinates who were randomly divided in 2 groups of 35 each. In group 1, patients underwent inferior nas...

INTRODUCTION It is common in some cryosurgical procedures to rely on freeze-thaw cycle(s) to destroy undesirable tissues. Most research in cryosurgery focuses on the freezing process and much less attention has been paid to thawing or re-warming. However, as ice melts during thawing, the extracellular solution can become locally hypotonic, driving water into cells, resulting in cell expansion a...

BACKGROUND Cryosurgery is an efficient therapeutic technique used to treat benign and malignant cutaneous diseases. The primary active mechanism of cryosurgery is related to vascular effects on treated tissue. After a cryosurgical procedure, exuberant granulation tissue is formed at the injection site, probably as a result of angiogenic stimulation of the cryogen and inflammatory response, part...

This study constitutes the advanced stage of an ongoing project for the development of cryosurgical devices and techniques for breast cryosurgery. The current study focuses on the long-term follow-up post-cryosurgery in a sheep breast model. Results of this study indicate that the cryotreatment site in a sheep breast model cannot be identified up to 5 months post-cryosurgery by means of ultraso...

BACKGROUND Cryosurgery is the most commonly used method to treat actinic keratosis (AK). Cryosurgical methods are not standardized. OBJECTIVE To examine differences in the spray techniques used for liquid nitrogen cryosurgery when treating AKs of the head, and the effect of these variations in technique on rates of complete clearance of AKs. MATERIALS AND METHODS Patients were those from th...

Typical probes that are used for cryosurgical applications manufactured from metals, since such materials as copper and brass feature high thermal conductivity at low temperatures enable rapid growth of an ice ball in living tissues. Due to a favorable combination properties, sapphire could be also widely tissue cryoablation. In this paper, probe is experimentally compared with metal ones. Usin...

Cutaneous cryosurgery refers to localized application of freezing temperatures to achieve destruction of skin lesions. It can be used to treat a broad range of benign and premalignant skin conditions, and certain malignant skin conditions, with high cure rates. Cellular destruction is accomplished by delivery of the cryogen via dipstick, probe, or spray techniques. It is widely used in primary ...

not available in our country, and surgery, in which recurrence rates after wide excision are lower than after local excision. Radiotherapy has been used only rarely for BD of the digit and has been delivered using various techniques (radioactive molds of gold or radon seeds, external beam therapy, photon radiotherapy using a water bath), as have laser carbon dioxide, photodynamic therapy, and t...