Abstract Background This study aimed to define clusters of disease activity and prognostic factors the course in a well-characterized cohort children with Crohn’s (CD). Methods All patients CD identified from SIGENP IBD registry follow-up at least 5 years 6-monthly evaluation were included. Active was defined for each yearly semester as follows: clinical (wPCDAI≥12,5 or MINI index ≥8), need tre...

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BACKGROUND: Crohns disease is an incurable progressive condition of the gastrointestinal tract in which up to 90% patients undergo one or more surgical interventions during their lifetime. Despite active development and implementation new techniques for treatment disease, incidence postoperative complications remains high, i.e., 25%30%. Until now, influence various factors on outcomes choice di...