background: considering the unknown etiology of inflammatory bowel disease (ibd), the epidemiologic evaluation may help to identify the causative agents of the disease. genetic (ethnic) and environmental (e.g., geographic) factors in iran may influence the incidence of the disease. the objective of this study was toâ  determine the demographic and clinical characteristics of the ibd in the city...

Numerous similarities between Crohn's disease and sarcoidosis are being reported. Because of previous findings of culturable mycobacteriophage in the serum of many patients with sarcoidosis, mycobacteriophages were sought in serum of patients with Crohn's disease. No difference was found in the frequency of positive cultures between patients with Crohn's disease and normal control subjects.

The typical macroscopic features of Crohn's disease have been well described and are widely regarded as sufficient to diagnose the disease at laparotomy. We report six patients undergoing laparotomy for symptomatic Crohn's disease, shown radiologically, who were found to have macroscopically normal small bowel despite careful examination of the bowel by an experienced surgeon. In four cases res...

P a t i e n t s 328 patients who were ≥ 18 years of age and had Crohn colitis or ileocolitis in complete remission (Crohn disease activity index [CDAI] ≤ 150) for ≥ 1 month before randomization. Exclusion criteria were receipt of steroid, azathioprine, or other immunosuppressive therapy within 8 weeks of the start of treatment; antibiotic therapy ≥ 1 month; potential for pregnancy or lactation;...

INTRODUCTION AND OBJECTIVE Patient preferences with respect to available therapies must be taken into account if the quality of care of patients with Crohn´s disease is to be improved. The objective was to develop the IMPLICA preferences questionnaire for Crohn´s disease patients treated with biological therapies. METHODS As per standard methodology, the questionnaire was developed in Spanish...

Seventeen pairs of identical twins concordant for Crohn's disease have been recorded (Table I). We describe a further set of affected twins unusual in that the disease developed simultaneously and at the same site in each patient at a time when they had been living in different environments for 6 years. As in a minority of previous reports (Crismer et al., 1963; Goldstein et al., 1976; Morichau...