Crimean-Congo hemorrhagic fever (CCHF) is an emerging zoonotic disease in India and requires immediate detection of infection both for preventing further transmission and for controlling the infection. The present study describes development, optimization, and evaluation of a novel molecular beacon-based real-time RT-PCR assay for rapid, sensitive, and specific diagnosis of Crimean-Congo hemorr...

conclusions unexpected complications may be seen during the course of cchf. patients must be closely followed up. case presentation a 49-year-old male dealing with livestock husbandry was admitted to ankara training and research hospital with three days of complaints including fever, malaise, headache, myalgia, nausea, vomiting, diarrhoea and hematuria. laboratory findings (thrombocytopenia and...

introduction crimean-congo hemorrhagic fever (cchf) is a viral hemorrhagic fever caused by infection with a tick-borne virus from the family of bunyaviridae. this viral hemorrhagic fever is found throughout central asia, southern europe, africa and the middle east. transmission to humans occurs through contact with infected animals or tick bite. the first human cases of infectious hemorrhagic f...

introduction crimean-congo hemorrhagic fever (cchf) is an acute viral zoonotic disease, which is endemic in vast geographic areas including the middle east. the causative agent, crimean-congo hemorrhagic fever virus (cchfv), is a nairovirus, which is mainly transmitted to human from infected hard ticks and viremic livestock. discussion given that viremic livestock are the main source of cchf ou...

background crimean-congo hemorrhagic fever (cchf) was a rare disease in iran before 1999. during the last 15 years, it has been reported from different provinces of iran, mostly from southeastern iran. objectives this study aimed to evaluate the factors associated with poor outcome in children and adolescents with cchf. patients and methods we studied all files of children (age < 19 years old) ...

conclusion we recommend that in outbreaks of cchf, care to prevent airborne transmission should be kept in mind. patient and method by a nosocomial transmission of crimean-congo hemorrhagic fever (cchf), a health care worker was infected in december 2008 due to a re-emerging outbreak of cchf in fars province, iran. after admission of probable cchf cases in a local hospital, one of the nurses co...

background: crimean-congo hemorrhagic fever virus (cchfv) belongs to genus nairovirus and family bunyaviridae. the main aim of this study was to investigate the extent of recombination in s-segment genome of cchfv in iran. methods: samples were isolated from iranian patients and those available in genbank, and analyzed by phyloge­netic and bootscan methods. results: through comparison of the ph...

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by an arbovirus, a member of the Nairovirus genera of Bunyaviridae family, one of the viral hemorrhagic fever causes and can be transmitted to humans by Hyalomma tickbite, by exposure to infected blood and fomites of patient with CCHF or contact with animal tissue in viremic phase, which was first recognized during a large ou...

introduction : this study was aimed to investigate the effects of risk factors, and environmental and climatic factors a ffecting the occurrence of crimean-congo hemorrhagic fever (cchf) in iran. we used temporal modeling to predict the future occurrence of the disease in the country . methods : we analyzed the data of 165 cchf patients from all over iran (e xcept the districts zabol and zaheda...

background: crimean congo hemorrhagic fever (cchf) is an acute febrile haemorrhagic disease. this study was conducted to ascertain the infection status amongst slaughterhouse workers in iran's north-eastern provinces (razavi and northern and southern khorasan), so that analysis of the results could help clarification of the epidemiology of this disease in the aforementioned provinces and easter...