background and aims. the high prevalence of helicobacter pylori among the microorganisms isolated from the oral environment brings up the question of whether oral cavity acts as a reservoir for this bacterium. the aim of the present study was to determine and compare the prevalence of h. pylori in gingival crevicular fluid (gcf) of patients with chronic periodontitis (cp) as an infectious disea...

background and aims. changes in the balance of sexual hormones during pregnancy decrease gingival crevicular fluid levels of interleukin-6 and the resistance of gingival tissue against inflammations. hormonal contraceptives are agents that are based on the effects of gestational hormones and simulate a state of pregnancy; therefore, they prevent ovulation. this study evaluates the effect of the...

Matrix metalloproteinases (MMPs), the key enzymes responsible for matrix degradation, are derived from polymorphonuclear leukocytes during the early stages of periodontitis. The aim of this study was planned to determine the levels of GCF (gingival crevicular fluid) matrix metalloproteinase-8 (MMP-8) and metalloproteinase-9 (MMP-9) patients with periodontitis and in healthy controls. Levels of ...

INTRODUCTION Pathogenesis and some characteristics of periodontitis cannot be fully explained by bacterial etiology alone. Herpes viruses may bridge the gap between clinical characteristics and molecular understanding of periodontal destruction. OBJECTIVE The aim of this study was to investigate the prevalence of herpes simplex virus type 1 (HSV-1) in gingival crevicular fluid (GCF) of health...

Recommended Citation Tymkiw, Keelen D.. "The influence of smoking on cytokines in the gingival crevicular fluid in patients with periodontal disease." MS

INTRODUCTION Gingivitis is a frequent inflammatory process of the gum tissue that is mainly caused by the accumulation of plaque. The immune response against inflammatory processes is regulated in part by cytokines. AIMS Given that a continuous inflammation exists in gingivitis, it would be logical to assume that the interleukins will be altered locally in those patients. Therefore, the aim o...

OBJECTIVES Histatin, with its anti bacterial, anti protease, and wound closure stimulating property might influence the pathogenesis of periodontal disease. This study assessed the presence of histatin in gingival crevicular fluid (GCF); the levels of salivary and GCF histatin in periodontal disease. MATERIAL AND METHODS It was a cross sectional study that included systemically healthy forty ...