نتایج جستجو برای: creb3 protein

تعداد نتایج: 1234699  

2013
Rui Zhang Noreen Rapin Zhengxin Ying Erika Shklanka Timothy W. Bodnarchuk Valerie M. K. Verge Vikram Misra

Cells respond to perturbations in the microenvironment of the endoplasmic reticulum (ER), and to the overloading of its capacity to process secretory and membrane-associate proteins, by activating the Unfolded Protein Response (UPR). Genes that mediate the UPR are regulated by three basic leucine-zipper (bLZip) motif-containing transcription factors - Xbp1s, ATF4 and ATF6. A failure of the UPR ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Rieko Nishimura Masayuki Ohmori Hironori Fujita Masayoshi Kawaguchi

The developmental program of nodulation is regulated systemically in leguminous host species. A mutant astray (Ljsym77) in Lotus japonicus has lost some sort of its ability to regulate this symtem, and shows enhanced and early nodulation. In the absence of rhizobia, this mutant exhibits characteristics associated with defects in light and gravity responses. These nonsymbiotic phenotypes of astr...

Journal: :Plant physiology 2006
Michael G Muszynski Thao Dam Bailin Li David M Shirbroun Zhenglin Hou Edward Bruggemann Rayeann Archibald Evgueni V Ananiev Olga N Danilevskaya

Separation of the life cycle of flowering plants into two distinct growth phases, vegetative and reproductive, is marked by the floral transition. The initial floral inductive signals are perceived in the leaves and transmitted to the shoot apex, where the vegetative shoot apical meristem is restructured into a reproductive meristem. In this study, we report cloning and characterization of the ...

Journal: :Journal of cell science 2010
Chi-Ping Chan To-Yuen Mak King-Tung Chin Irene Oi-Lin Ng Dong-Yan Jin

CREB-H is a liver-enriched bZIP transcription factor of the CREB3 subfamily. CREB-H is activated by intramembrane proteolysis that removes a C-terminal transmembrane domain. Aberrant expression of CREB-H is implicated in liver cancer. In this study we characterized N-linked glycosylation of CREB-H in the luminal domain at the C-terminus. We found that CREB-H is modified at three N-linked glycos...

Journal: :Canadian Journal of Animal Science 2021

A candidate-gene high density SNP scanning approach was used to investigate the swine LUMAN/CREB3 locus for polymorphisms in 232 Ontario Yorkshire and 29 Chinese Meishan pigs. Inter- intra-breed differences genetic diversity were characterized. In breed, eight variations (three coding five non-coding) identified. Two LD blocks (550bp ~4kb length) featuring two three haplotypes, respectively, re...

Journal: :Human molecular genetics 2003
Clelia Tiziana Storlazzi Fredrik Mertens Antonio Nascimento Margareth Isaksson Johan Wejde Otte Brosjo Nils Mandahl Ioannis Panagopoulos

The FUS gene at 16p11 fuses with DDIT3 and ATF1 as the result of translocations with chromosome band 12q13 in myxoid liposarcoma and angiomatoid fibrous histiocytoma, respectively, and with ERG as the result of a t(16;21)(p11;q22) in acute myeloid leukemia. We here show that a t(7;16)(q33;p11) in two cases of low grade fibromyxoid sarcoma fuses the FUS gene to BBF2H7, a previously uncharacteriz...

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