نتایج جستجو برای: cr 40
تعداد نتایج: 376110 فیلتر نتایج به سال:
Caloric restriction (CR) inhibits many neoplastic diseases in rodents, yet the biochemical mechanism(s) for these effects are poorly understood. We have examined the effects of ad libitum (AL) feeding with 25 or 40% CR on the promotion of 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in virgin female Sprague-Dawley rats. Further, we have also studied the influence of chronic CR o...
Intermediate-energy Coulomb excitation measurements are performed on the N ≥ 40 neutron-rich nuclei (66,68)Fe and (64)Cr. The reduced transition matrix elements providing a direct measure of the quadrupole collectivity B(E2;2(1)(+) → 0(1)(+)) are determined for the first time in (68)Fe(42) and (64)Cr(40) and confirm a previous recoil distance method lifetime measurement in (66)Fe(40). The resul...
In vitro toxicological influence of culture filtrates of Fusarium oxysporum f. sp. lycopersici (Sacc.) Snyder & Hans was investigated on seed germination, seedling growth and physiology of tomato (Lycopersicum esculentum Mill.) under chromium(VI) stress. Original culture filtrates of the fungus and three concentrations of Cr(VI) viz. 50, 75 and 100 mg L1 were used in laboratory bioassays either...
BACKGROUND Severe calorie restriction (CR) is shown to improve or even reverse β-cell dysfunction in patients with obesity and type 2 diabetes mellitus. However, whether mild to moderate CR can reverse β-cell dysfunction induced by obesity and the underlying mechanism remain unclear. Autophagy plays an important role in maintaining mass, architecture and function of β-cells. While the impact of...
Caloric restriction (CR) inhibits many neoplastic diseases in rodents, yet the biochemical mechanism(s) for these effects are poorly understood. We have examined the effects oÃ-ad libitum (AL) feeding with 25 or 40% CR on the promotion of 7,12-dimethylbenz(a)anthracene-induced mam mary tumorigenesis in virgin female Sprague-Dawley rats. Further, we have also studied the influence of chronic CR ...
Calorie restriction (CR) increases average and maximum lifespan and exhibits an apparent beneficial impact on age-related diseases. Several studies have shown that CR initiated either in middle or old age could improve ischemic tolerance and rejuvenate the aging heart; however, the data are not uniform when initiated in young. The accurate time to initiate CR providing maximum benefits for card...
Calorie restriction (CR) has been repeatedly shown to prevent cancer, diabetes, hypertension, and other age-related diseases in a wide range of animals, including non-human primates and humans. In rodents, CR also increases lifespan and is a powerful tool for studying the aging process. Recently, it has been reported in mice that dietary fat plays an important role in determining lifespan exten...
The region of neutron-rich Cr isotopes has garnered much attention in recent years due to a rapid onset collectivity near neutron number $N=40$. We report here on the first $\ensuremath{\gamma}$-ray spectroscopy beyond $({4}_{1}^{+})$ state $^{62,64}\mathrm{Cr}$, using nucleon removal reactions from several projectiles within rare-isotope beam cocktail. A candidate for ${6}^{+}$ $^{64}\mathrm{C...
To investigate the role mitochondrial membrane lipids play in the actions of calorie restriction (CR), C57BL/6 mice were assigned to four groups (control and three 40% CR groups) and fed diets containing soybean oil (also in the control diet), fish oil, or lard. The fatty acid composition of the major mitochondrial phospholipid classes, proton leak, and H(2)O(2) production were measured in musc...
Thermodynamic properties of complexes of Congo Red (CR) dye with amyloid (A) peptides were studied by both absorption spectroscopy and isothermal titration calorimetry (ITC). Based on the absorption spectrum for the formation of CR-Aβ complexes in phosphate buffered saline solution (pH 7.4), van’t Hoff plots over a temperature range of 10oC to 70oC were created for CR-Aβ1-40, -Aβ12-28, and -...
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