The objective of hazards (lifetime) analysis is to advance and promote statistical science in the various applied fields that deal with lifetime (survival) data including: actuarial science and reliability engineering. The lifetime data analysis provides special techniques that are required to compare the risks for failure. Bayesian semi-parametric methods have been applied to survival analysis...

Simulation studies present an important statistical tool to investigate the performance, properties and adequacy of statistical models in pre-specified situations. One of the most important statistical models in medical research is the proportional hazards model of Cox. In this paper, techniques to generate survival times for simulation studies regarding Cox proportional hazards models are pres...

MOTIVATION There has been an increasing interest in expressing a survival phenotype (e.g. time to cancer recurrence or death) or its distribution in terms of a subset of the expression data of a subset of genes. Due to high dimensionality of gene expression data, however, there is a serious problem of collinearity in fitting a prediction model, e.g. Cox's proportional hazards model. To avoid th...

For statistical inference on regression models with a diverging number of covariates, the existing literature typically makes sparsity assumptions inverse Fisher information matrix. Such assumptions, however, are often violated under Cox proportion hazards models, leading to biased estimates under-coverage confidence intervals. We propose modified debiased lasso method, which solves series quad...

Cox's proportional hazards model is often t to grouped survival data, i.e. occurrence/exposure data over given time intervals and covariate strata. We derive a Sheppard correction for the bias in the grouped data analogue of Cox's maximum partial likelihood estimator. This is done via a large sample theory in which the covariate strata and time intervals shrink as the sample size increases.

INTRODUCTION The Irish ALS register is a valuable resource for examining survival factors in Irish ALS patients. Cox regression has become the default tool for survival analysis, but recently new classes of flexible parametric survival analysis tools known as Royston-Parmar models have become available. METHODS We employed Cox proportional hazards and Royston-Parmar flexible parametric modeli...

The recent literature on the duration of trade has predominantly analyzed the determinants of trade flow durations using Cox proportional hazards models. The purpose of this paper is to show why it is inappropriate to analyze the duration of trade with continuous-time models such as the Cox model, and to propose alternative discrete-time models which are more suitable for estimation. Briefly, t...