نتایج جستجو برای: corneal nociception
تعداد نتایج: 31835 فیلتر نتایج به سال:
Introduction : Horizontal corneal diameter is one of the diagnostic factors in some ophthalmic diseases. At present American Newborn horizontal corneal diameter is considered as our normal value in Iranian ones, while it may be quite different in Iranian newborns. Early diagnosis is critical in some ophthalmic diseases such as congenital glaucoma and awareness of normal corneal diameter is es...
ABSTRACT The purpose of this study was the evaluation of cycloplegic effect of homatropine 2% on central corneal curvature and power. 43 volunteers who participated in the study were examined. Thirty-nine of them (28 men and 11 women) which had normal eyes with visual acuity of 20/20 and a mean age of 29.6 ± 6.7 years were selected. Then corneal topography was performed on both eyes. After per...
This study aimed to assess the possible topical antinociceptive activity of Vanillosmopsis arborea Baker essential oil (EOVA) and to clarify the underlying mechanism, using the acute model of chemical (eye wiping) nociception in mice. EOVA (25 to 200 mg/kg; p.o. and topical) evidenced significant antinociception against chemogenic pain in the test model of formalin-induced neuroinflammatory pai...
Various techniques are applied to reduce the severity of postoperative pain and discomfort in patients. The purpose this research work was evaluate effectiveness safety Dexmedetomidine as an adjuvant anesthesia ophthalmic surgery. study included 80 patients who underwent corneal transplantation on basis Dnepropetrovsk Regional Clinical Ophthalmologic Hospital. Patients were divided into 2 group...
The parafascicular nucleus (PFN) of thalamus, as a supraspinal structure, has an important role in processing of nociceptive information. In addition, μ-opioid receptor contributes to supraspinal modulation of nociception. In the present study, the effects of microinjection of naloxone (a non-specific opioid-receptor antagonist) and naloxonazine (a specific μ-opioid receptor antagonist) were in...
Nociception, the sensory mechanism that allows animals to sense and avoid potentially tissue-damaging stimuli, is critical for survival. This process relies on nociceptors, which are specialized neurons that detect and respond to potentially damaging forms of energy - heat, mechanical and chemical - in the environment. Nociceptors accomplish this task through the expression of molecules that fu...
Abstract Threat-induced pain modulation can increase survival by amplifying physiological and behavioral reactions toward danger. Threat also modulate spinal nociception, suggesting engagement of endogenous top-down circuitry. A unique method to assess nociception is via reflex receptive fields (RRF) associated with the nociceptive withdrawal (NWR, a protective spinally-mediated reflex...
Introduction & Objective: Corneal ulcer is one of the most important medical emergencies that in the absence of on time diagnosis and treatment can lead to loss of vision. Therefore, identification of microorganisms and their response to drugs in each region is important. The aim of this study was to determine the most common organisms that cause keratitis and antibiotic sensitivity in this reg...
In the present study, the effects of the acute and chronic oral administrations (po) of curcumin in the absence and presence of morphine and naloxone was investigated on the sensation of acute corneal pain in rats. Acute corneal pain was induced by the local application of hypertonic saline (5 M NaCl) on the corneal surface, and the number of eye wipes was then counted for 30 s. Subcutaneous (s...
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