BACKGROUND The effect of corticosteroid therapy on corneal wound healing is controversial. The objective of this study was to evaluate the effects of combination therapy with dexamethasone and acetylcysteine at different times and durations on experimentally-induced corneal wounds and haze in rabbits. METHODS Eighteen adult New Zealand white rabbits were divided into three groups of six each....

AIM To assess superficial lamellar keratectomy augmented by excimer laser smoothening with sodium hyaluronate 0.25%, for the management of superficial corneal opacities. METHODS Consecutive procedure performed in 14 eyes (13 patients) with an automated microkeratome and excimer laser phototherapeutic keratectomy (PTK) smoothening using sodium hyaluronate 0.25%. MAIN OUTCOME MEASURES UCVA, B...

purpose: to report the results of photorefractive keratectomy (prk) with mitomycin-c (mmc) to correct myopia and astigmatism in patients who had previously undergone penetrating keratoplasty (pkp). methods: thirty-eight eyes of 32 patients underwent prk with mmc to correct astigmatism and myopia following pkp. result: mean spherical equivalent (se) was -5.2±4.7 d (diopter) and mean astigmatism ...

purpose : to compare the postoperative results of epi-lasik and photorefractive keratectomy-mitomycin (prk-mitomycin) in patients with moderate to high myopia methods : for this double-blind clinical trial, samples were randomly selected among those subjects above 20 years of age who were visited for myopia correction and had a spherical equivalent between -4 to -8 d. we randomly performed prk-...

purpose: to evaluate the 8-year results of excimer laser photorefractive keratectomy (prk) for myopia in terms of safety, stability and late complications. methods: of 203 myopic patients who underwent prk with single-step method using nidek ec-5000 excimer laser with 5-6 mm ablation zones at basir eye center, tehran-iran from 1996 to 1998, 179 eyes of 98 patients who completed 8 years of follo...

PURPOSE: To report persistent subepithelial haze in two patients following femtosecond LASIK associated with creation of a thin fl ap. METHODS: Subepithelial haze was assessed by slit-lamp photography, high-resolution Scheimpfl ug imaging, and corneal confocal microscopy. RESULTS: Two patients showed distinct subepithelial haze and reduced corrected distance visual acuity at 3 months after LASI...

AIM To evaluate the in vivo confocal microscopic corneal features seen in patients who underwent Descemet's stripping with endothelial keratoplasty (DSEK) and to correlate these findings with the postoperative best spectacle-corrected visual acuity (BSCVA) obtained at the time of confocal microscopy. METHODS Observational case series. A review of charts and confocal microscopy images and vide...

BACKGROUND To evaluate the in vivo corneal changes using in vivo confocal microscopy (IVCM) and anterior segment optical coherence tomography (AS-OCT) in patients with Fuchs' dystrophy who underwent Descemet stripping automated endothelial keratoplasty (DSAEK) and the relationship between these changes and the postoperative visual recovery up to 1-year follow-up. METHODS Before DSAEK and 1 da...

PURPOSE To compare the effect of topical 0.1% indomethacin solution versus 0.1% fluorometholon acetate in the early postoperative period after LASEK treatment. METHODS One hundred thirty-five patients undergoing LASEK, having been randomized in a double-masked manner into 2 groups (1 receiving indomethacin and 1 fluorometholon), were evaluated 2-4 days before and 4 days after treatment. We ex...

To the Editor: Flap creation is the most crucial step of LASIK and the introduction of the femtosecond laser led to the production of uniform flaps enhancing the accuracy and reproducibility of LASIK.1,2 However, intrastromal corneal opacity (such as scar and haze) raised controversies regarding the efficacy of the technique in such cases because it can interfere with laser tissue disruption, c...