PURPOSE To characterize corneal epithelial cells separated from limbus in vivo by transplantation of a stainless steel ring with or without creating a defect inside the ring. METHODS A stainless steel ring (diameter, 8 mm; width, 300 μm; depth, 250 μm) was transplanted into rabbit corneal stroma using 10-0 nylon interrupted suture after cutting to a 250 μm depth by corneal vacuum trephine (di...

The mitotic rate and goblet cell content of conjunctival epithelium following total or central corneal epithelial removal using n-heptanol was measured to determine how the conjunctival epithelium responds to injury and whether conjuctiva responds to central corneal epithelial loss. One day following a wound that removed corneal, limbal, and 1-2 mm of bulbar conjunctival epithelium, the mitotic...

PURPOSE To evaluate the influence of peripheral ocular topography, as evaluated by optical coherence tomography (OCT), compared with traditional measures of corneal profile using keratometry and videokeratoscopy, on soft contact lens fit. METHODS Ocular surface topography was analyzed in 50 subjects aged 22.8 years (SD ±5.0) using videokeratoscopy (central keratometry, corneal height, and sha...

Corneal Regeneration In article 2300192 by Lixin Xie, Qingjun Zhou, and co-workers, a photoreactive adhesive hydrogel that mimics the extracellular matrix (mainly composed of gelatin hyaluronic acid) is designed to treat large-diameter (≥6 mm) corneal defects, which effectively promotes epithelial, stromal, neural regeneration while preventing scar formation. It also holds great improvement exp...

PURPOSE To evaluate the relationship between the horizontal ciliary sulcus diameter and anterior chamber diameter measured by 35 MHz ultrasound biomicroscopy (UBM) and the horizontal corneal diameter (white to white [WTW]) measured by scanning-slit topography and to assess the repeatability (intraexaminer difference) of the 2 methods. SETTING Department of Orthoptics and Visual Science, Kitas...

PURPOSE To determine the distribution of anterior eye biometry indices, such as keratometry pachymetry, anterior chamber depth (ACD), pupil diameter, and corneal diameter, as measured by Orbscan instrument in a young Iranian population. METHODS A cross-sectional study was conducted, and subjects were selected through multistage cluster sampling from the students of Mashhad University of Medic...

The purpose of this study is to demonstrate the feasibility of DALK using a decellularized corneal matrix obtained by HHP methodology. Porcine corneas were hydrostatically pressurized at 980 MPa at 10°C for 10 minutes to destroy the cells, followed by washing with EGM-2 medium to remove the cell debris. The HHP-treated corneas were stained with H-E to assess the efficacy of decellularization. T...

Purpose: To determine if the mean horizontal white-towhite (WTW) corneal diameter, measured intraoperatively with calipers, of a population of cataract surgery patients differs from the currently accepted normal WTW range of greater than 11.0 and less than 13.0 mm. In addition, we compared manual caliper measurements with those with IOLMaster. Setting: Cincinnati Eye Institute, Cincinnati OH. D...

AIM To evaluate differences in flap thickness resulting from use of an Alcon Wavelight FS200 femtosecond laser and a MORIA SBK microkeratome when making a 110-µm-thick corneal flap and to identify the potential factors that affect corneal flap thickness. METHODS A prospective case study was performed on 120 eyes of 60 patients who were divided into two groups for LASIK, each group consisting ...

BACKGROUND To determine the effect of an ethanol-treated mid-peripheral epithelium on wound healing of the corneal epithelium. METHODS Epithelial removal was performed on 18 rabbit eyes, which were divided into three groups of six eyes each as follows: group 1, an 8.0-mm diameter treated with balanced salt solution (BSS) and an 8.0-mm removal; group 2, an 8.0-mm diameter treated with 20% etha...