sulfur mustard, a bifunctional alkylating agent, causes severe eye injury. the injury is a result of late inflammation, which is mediated by prostaglandins. theoretically, inhibition of prostaglandins by reagents such as indomethacine could result in alleviation of clinical adverse effects. in this study, the protective effect of topically applied indomethacine against sulfur mustard toxicity w...

purpose: to report the confocal microscopic features of endothelial vacuolation in donated corneas and to confirm the observed changes by transmission electron microscopy. methods: confocal and transmission electron microscopy were performed on donated corneas with endothelial vacuole formation on slitlamp biomicroscopy. the ultrastructural findings were also compared with those of a normal-loo...

purpose: to report a case of isolated corneal squamous cell intraepithelial neoplasia in a patient with unilateral dry eye symptoms. case report: a 48 year old man presented with history of thermal corneal injury in his left eye two years ago, with decreased visual acuity and dry eye symptoms a short time thereafter. he was treated for dry eye with no improvement in symptoms. upon presentation,...

The effect of VSV infection in rabbit eye was investigated. The findings indicated that maximum virus growth in the rabbit cornea coincided with peak keratitis on postinfection day 1. Thereafter, keratitis was generally not observed, whereas infectious virus was detected in the cornea through day 6. Primary virus infection in the cornea of one eye produced serum-neutralizing antibody which did ...