introduction: human leukocyte antigen (hla) genes are the most polymorphic loci in the human genome. they predict the outcome of transplantation by detecting self from non-self antigens. the best use of hla typing is to find a hla-match donor for bmt candidate patients. evidence suggests that matching unrelated donors and recipients for hla-a, -b and -drb1 loci is a prediction for an improved o...

umbilical cord blood (ucb) as a source of hematopoietic stem/progenitor cells (hspcs) used for umbilical cord blood transplantation (ucbt). the main obstacle in application of this source as an appropriate source of hspcs is low volume of this product. so ex vivo expansion of these cells in a microenvironment which mimic body condition is important. in current study we designed biocompatible mi...

background: tumor necrosis factor alpha (tnf-α) is a primary mediator of immune regulation and might be required in the early stages of dc development from cd34+ cells. however, details of optimal timing of exposure to tnf-α in dc development process in monocytes or non-purified hematopoitic cells are still lacking and clear benefits of this approach to the development of dcs remain to be valid...

background the aim of this study was the ex vivo expansion of umbilical cord blood hematopoietic stem cells on biocompatible nanofiber scaffolds. materials and methods cd133+ hematopoietic stem cells were separated from umbilical cord blood using midimacs (positive selection) system by means of monocolonal antibody cd133 (microbeads) subsequently, flowcytometry method was done to assess the pur...

conclusions in a current study based on increasing maternal age, the hdl-c level in cord blood was decreased which is an independent risk factor for cvds in adulthood. results a statistically significant negative correlation was observed between cord blood hdl-c and maternal age (r = -0.18, p <0.01). there was no relationship between other lipids and lipoproteins with maternal age. our findings...

Cord blood is the blood that remains in the umbilical cord and placenta following birth, which is usually discarded It contains red blood cells, white blood cells, platelets, and plasma, like blood. In addition, cord blood is a rich source of stem cells that may have potentially lifesaving benefits for your baby and family. The cord blood of baby serves as an abundant source of stem cells. Thes...

background: dendritic cells (dcs) are the most potent stimulators of primary t cell responses and play a key role in immune reactions after stem cell transplantation. very little is known about the cord blood (cb) dendritic cells and their potential involvement in the low incidence and lower severity of acute graft-versus-host disease after cb transplantation.   objectives: the aim of this stud...

UNLABELLED BACKGROUND Condom catheters are indicated in spinal cord injury patients in whom intravesical pressures during storage and voiding are safe. Unmonitored use of penile sheath drainage can lead to serious complications. CASE REPORT A 32-year old, male person, sustained complete paraplegia at T-11 level in 1985. He had been using condom catheter. Eleven years after sustaining spina...

introduction: in 1989, the first successful umbilical cord blood transplantations (ucbts) was reported in a boy with fanconi's anemia, using umbilical cord (ucb) of his hla matched sister. cord blood transplantation is a good substitute for bone marrow or peripheral blood transplantation especially for children and small body size adults. methods: between 1998 and 2007 ,14 children(10 boys and ...

conclusions we found a relatively high value of tc and tg in our study. considering the relationship between high levels of lipids in the neonatal period and coronary artery disease in the adult population, we recommend future cohort studies for this statistical society. results of the 174 neonates, 97 were female. vaginal delivery was recorded in 79.8%. there were no significant differences re...