Introduction ABO hemolytic disease of the newborn is most common cause of neonatal jaundice; previous studies have shown a poor correlation between serologic tests and clinical course in affected infants. The aim of this study was to identify the value of direct and indirect Coombs’ immunohematological tests, to identify the incidence of hemolytic disease in newborns (ABO-HDN). Methods : This  ...

Introduction: Brucellosis is a zoonotic infectious disease with worldwide distribution, especially in the south and central American countries, the Middle-East and the Mediterranean areas. Knee prosthesis infection due to Brucella spp. is very rare with the first case reported in 1991 and the ninth case reported in 2010. Case Presentation: Here is reported a case of a 68-year-old female patient...

Although neurological symptoms in brucellosis are frequent, central nervous system (CNS) involvement is uncommon. A 42-year-old man was admitted with an episode of faint without loss of consciousness, right hemi paresis, diplopia and headache lasting for four days. The neurological examination revealed left hemi paresis. Limitation of gazing in left eye in lateral view was seen (partial paresis...

The brucellosis with multi-organ involvement in a patient with a history of the composite aortic graft (Bentall procedure) and Hepatitis B infection is rare. A 35-year-old man presented to us with fever and loss of consciousness. Four years ago, he was IDU and underwent cardiac surgery because of endocarditis. Recently lumbar spondylodiscitis was diagnosed. The Wright (1/320) and Coombs Wright ...

The Coombs test (Coombs, Mourant, and Race, 1945a, 1945b, 1946) has become popular as a sensitive and reliable method of detecting incomplete antibodies. The essential reagent is the serum of an animal (usually a rabbit) which has been immunized with human globulin. Potent rabbit sera sometimes show a prozone phenomenon (Wootton, 1950; Van Loghem, Kresner, Coombs, and Fulton Roberts, 1950). The...

OBJECTIVE To determine the usefulness of the hour-specific Bhutani et al bilirubin nomogram when applied to infants with Coombs-positive test results. DESIGN Retrospective chart review. SETTING Term nursery and neonatal intensive care unit of a university-affiliated hospital. PATIENTS All infants with A+ or B+ blood type born in our center from September 1, 2006, through August 31, 2008, ...

S EVERAL RECENT REPORTS have incriminated reticulocytes as the cause of “false positive” Coombs tests obtained in spontaneous or experimentally induced anemia.14 As reticulocytosis is frequently associated with the spontaneous Coombs positive hemolytic anemia which develops in NZB mice, and because the positive Coombs test has been used by Holmes and Burnet5T as the main basis for calling the c...

BACKGROUND A combination of the LISS/Coombs and enzyme methods is recommended for identifying unexpected antibodies. However, many laboratories in which tests are to be performed within the limits of medical fees covered by insurance, use only the LISS/Coombs method because the permissible medical fee is low as compared to the price of reagents required for both methods. The NaCl/Enzyme gel is ...

Introduction: A comparative study of blood cross match between gel card technique and conventional tube method wasundertaken on approx 1000 sample conducted in Sanjay Gandhi Memorial Hospital ,Rewa associated with Shyam shahmedical college Rewa .Material & Methods: most commonly conventional tube method are used widly. Now new technique of cross matching isintroduced . In th...