The delivery of drugs into systemic circulation via skin has generated much attention during the last decade. Transdermal therapeutic systems propound controlled release of active ingredients through the skin and into the systemic circulation in a predictive manner. Drugs administered through these systems escape first-pass metabolism and maintain a steady state scenario similar to a continuous...

conclusions intravenous administration of paracetamol immediately after knee arthroscopy improved postoperative pain, decreased analgesic administration, maintained stable hemodynamic parameters, had no complications related to opiates, no nausea and vomiting, and increased patient satisfaction and comfort in comparison to pca with morphine. results there was no significant difference regarding...

Background: Spinal anesthesia is an accepted technique in elective cesarean sections. However, hypotension, resulted from sympathectomy is a common problem, especially in pregnant women. Prevention of this complication by sympathomimetic agents is of potential clinical significance. The aim of this study is to compare the effect of prophylactic infusion of Phenylephrine versus Ephedrine in the ...

objective absence status epilepticus (ase) is a common form of nonconvulsive status epilepcticus. it is  characterized by loss of consciousness with spike and wave discharges in eeg simultaneously. the most effective treatment of ase is diazepam, either infusion or in divided doses; the former is more expensive since patients must be admitted in an intensive care unit. the aim of this study was...