introduction: it was shown in a previous study, that mcpip, a cilostamide derivative, increased atrial contraction force without changing contraction rate. to improve this property, two new derivatives of cilostamide were synthesized and their effects on pde3 activity and isolated rat atria contraction were investigated. methods: the inhibitory effect of each compound on pde3 enzyme was determi...

boujari [5] proved a fixed point theorem with an old version of the integraltype contraction , his proof is incorrect. in this paper, a new generalizationof integral type contraction is introduced. moreover, a fixed point theorem isobtained.

A dynamical system is called contractive if any two solutions approach one another at an exponential rate. More precisely, the dynamics contracts lines This property implies highly ordered asymptotic behavior including entrainment to time-varying periodic vector fields and, in particular, global stability for time-invariant fields. Contraction theory has found numerous applications systems and ...

We discuss about the generalized $F$-contraction mappings in partially ordered metric spaces. For this, we first introduce the notion of ordered weakly $F$-contraction mapping. We also present some fixed point results about this type of mapping in partially ordered metric spaces. Next, we introduce the notion of $acute{mathrm{C}}$iri$acute{mathrm{c}}$ type generalized ordered weakly $F$-contrac...

in this paper, we give a new fixed point theorem forweakly quasi-contraction maps in metric spaces. our results extend and improve some fixed point and theorems in literature.

objectives in order to provide a pharmacological profile for some newly synthesized dihydropyridines, we investigated their effects on the isolated rat colon segments and the isolated rat atrium contractility. the tested compounds include alkyl ester analogues of nifedipine, in which the ortho-nitrophenyl group at position 4 is replaced by 2-alkylthio-1-benzyl-5-imidazolyl substituent, and nife...

objective: due to the frequent use of surface electromyography as a tool for the study of muscle function, to accurately compare electromyographic data from different muscles and different subjects, it is necessary to normalize the integrated data obtained from each muscle. the most common normalization technique is the use of maximum voluntary isometric contraction (mvic) of a predetermined is...