The aim of this study was to investigate the combined influence of 3 independent variables in the preparation of paclitaxel containing pH-sensitive liposomes. A 3 factor, 3 levels Box-Behnken design was used to derive a second order polynomial equation and construct contour plots to predict responses. The independent variables selected were molar ratio phosphatidylcholine:diolylphosphatidyletha...

The aim of the present study was to prepare, optimize and characterize ketoprofen proniosomes. The niosomes were prepared using a slurry method followed by in vitro evaluation after embedding the proniosomes-derived niosomes into a carbopol matrix. A central, composite Box-Wilson design was used for the optimization with the total lipid concentration (X1), surfactant loading (X2) and amount of ...

Austenitic stainless steel sheets have gained wide acceptance in the fabrication of components, which require high temperature resistance and corrosion resistance such as metal bellows used in expansion joints in aircraft, aerospace and petroleum industries. In the case of single pass welding of thinner sections of this alloy, Pulsed Current Micro Plasma Arc Welding (PCMPAW) has been found bene...

metal matrix composites have been widely used in industries, especially aerospace industries, due to their excellent engineering properties. however, it is difficult to machine them because of the hardness and abrasive nature of reinforcement elements like silicon carbide particles (sicp).in the present study, an attempt has been made to investigate the influence of spindle speed (n), feed rate...

Computed off-nucleus magnetic shielding isosurfaces and contour plots provide a feature-rich picture of aromaticity bonding breathe new life into Clar's aromatic sextet theory.

The concern is the analysis and display of data that is aggregate over geographic regions (such as census divisions) for phenomena that are felt to vary smoothly in space. In Brillinger (1990b) some spatial locally weighted analyses were provided for births taking place to women aged 25 to 29 in the years 1986 and 1987 for the province of Saskatchewan at the census division level. Various resul...

In the present study, 3 factorial design was used to investigate the combined influence of three independent variables in the preparation of Cytarabine liposomes by thin film hydration method. The process variables like rotation speed, temperature, vacuum applied and hydration time were kept constant through out the study. The formulation variables, Drug (Cytarabine) / Lipid [Phosphatidyl choli...

The study was conducted to determine the combined effect of birthweight and gestational age at birth on neonatal mortality using individually-identified livebirths. Logistic regression was used for studying the interactive effect of birthweight and gestational age on the individual probability of neonatal death. All livebirths from Chile in 2000 were included in a linked file. Odds ratio models...

the aim of this study was to explore the minimum amount of urea formaldehyde (uf) resin content and optimum particleboard density while maintaining boards’ quality to reduce production costs. board density at three levels (520, 620 and 720 kg m-3) and resin content (6, 7 and 8%) were variable parameters. stepwise multivariate linear regression models were used to evaluate the influence of board...

This reports the study on the flow behaviour, heat transfer and contamination distribution in a room. For this purpose the 3-D incompressible Navier-Stokes equations, energy equation and a mass transfer equation which model the concentration of contamination have been applied. For turbulence simulation the two equation standard k-  turbulence model was employed. By means of SIMPLE algorithm the...