The aims of this study were to investigate exposure-based treatments for cynophobia (dog phobia) and to test a newly developed hybrid imaginal exposure treatment that we have named active imaginal exposure. The treatment introduces an in vivo coping component to imaginal exposure whereby the patient physically performs coping responses to an imagined feared stimulus. Eighty-two participants mee...

The primordia of the thoracic imaginal discs of the Drosophila embryo originate as groups of cells spanning the parasegment boundary. We present evidence that the thoracic imaginal primordia are allocated in response to signals from the wingless (wg) and decapentaplegic (dpp) gene products. Rows of cells that express wg intersect rows of cells that express dpp to form a ladder-like pattern in t...

54 The aims of this study were to investigate exposure-based treatments for cynophobia (dog phobia) and 55 to test a newly developed hybrid imaginal exposure treatment that we have named active imaginal exposure. 56 The treatment introduces an in vivo coping component to imaginal exposure whereby the patient physically 57 performs coping responses to an imagined feared stimulus. Eighty-two part...

Dissociations between perceptual and imaginal neglect are typically investigated by using very different tasks (e.g. visual target cancellation vs. place descriptions). Here we report patients' performance on imaginal and perceptual tasks which shared identical stimuli and procedure, except for the modality of stimulus presentation. In different tasks, participants either saw towns/regions on a...

Drosophila minidiscs mutant larvae have smaller imaginal discs than wild-type larvae. However, transplantation experiments have revealed that minidiscs mutant imaginal discs can grow if cultured in non-mutant hosts. These data suggest that minidiscs is required in one or more non-imaginal tissues for synthesis and/or secretion of a diffusible factor that stimulates imaginal cell proliferation. ...

The fictional world imaginatively constituted during literary reading is sometimes compared with the imaginal world created during dreaming. At the core of both reading and dreaming may be the type of attentional adjustment that occurs when departures from expected events emerge in experience. During dreaming, markers of this attentional adjustment – and of the related transformations of dream ...

and clatter. The Italians call them buffone — clowns. The large white grubs feed on roots and can be a major pest of grass and potatoes. Now controlled by pesticides, they were once far more abundant locally. In 1574, adult cockchafers were so numerous in the Severn Valley that their drowned bodies blocked the wheels of watermills, the book describes. In parts of Europe, if not in Britain, the ...

The evolution of imaginal cells, or stem cell-like cells, contributed to the spectacular diversification of holometabolous insects, which undergo complete metamorphosis. The proliferation and differentiation of these imaginal cells is under the control of juvenile hormone (JH), but which patterning genes respond to JH is currently unknown. Here, the role of Hedgehog (Hh) signaling in the develo...

The components of the pupal cuticle are the main differentiation products synthesized by both the larval and adult epidermis during the prepupal period of Drosophila development. The pupal cuticle is formed in vitro by imaginal discs in response to a 6 h pulse of 20-hydroxyecdysone (20-HE). We previously described the isolation and initial characterization of four ecdysone-dependent genes (EDGs...