It is unknown whether short-term modulation of substrate supply affects cardiac performance in heart failure patients with chronic ischemic myocardium. The aim of this study was to determine whether modulation of myocardial substrate metabolism with insulin and free fatty acids (FFAs) affects contractile function of chronically stunned (CST) and hibernating (HIB) myocardium at rest and after ma...

Consider the triangle-free graph process, which starts from the empty graph on n vertices and in every step an edge is added that is chosen uniformly at random from all non-edges that do not form a triangle with the existing edges. We will show that there exists a constant c such that asymptotically almost surely no copy of any fixed finite triangle-free graph on k vertices with at least ck edg...

High-performance piezoelectricity in monolayer semiconducting transition metal dichalcogenides is highly desirable for the development of nanosensors, piezotronics and photo-piezotransistors. Here we report the experimental study of the theoretically predicted piezoelectric effect in triangle monolayer MoS2 devices under isotropic mechanical deformation. The experimental observation indicates t...

Subunit a of V-ATPase in the yeast Saccharomyces cerevisiae, in contrast to its other subunits, is encoded by two genes VPH1 and STV1. While disruption of any other gene encoding the V-ATPase subunits results in growth arrest at pH 7.5, null mutants of Vph1p or Stv1p can grow at this pH. We used a polyclonal antibody to yeast Stv1p and a commercially available monoclonal antibody to Vph1p for a...

Catestatin (CST), a chromogranin-A-derived peptide, is a potent endogenous inhibitor of the neuronal nicotinic acetylcholine receptor (nAChR). It exerts an anti-hypertensive effect by acting as a 'physiological brake' on transmitter release into the circulation. However, the mechanism of interaction of CST with nAChR is only partially understood. To unravel molecular interactions of the wild-ty...

In this paper, we investigate the behavior of strain gradient elasticity solutions around sharp edges body loaded by concentrated loads. We consider general Mindlin–Toupin (SGET) and several simplified models, including dilatation theory (DGET) couple stress (CST). framework a plane problem for an elastic wedge with prescribed tip displacement obtain analytical assessments field state apex. Inv...