نتایج جستجو برای: congenital leukemia
تعداد نتایج: 399984 فیلتر نتایج به سال:
BACKGROUND Emergency department workup of pediatric fever typically focuses on ruling out serious bacterial infection, but other disease processes can cause fever. Congenital leukemia is a rare but important cause of fever in neonates. We review the presentation, pathophysiology, and potential complications of congenital leukemia presenting to the emergency department as pediatric fever. CASE...
Congenital leukemia is a rare and poorly defined disease. Many authors define it as leukemia occurring from birth to four week. Others recognize it as being synonymous with leukemia of the neonatal period and infancy. It is commonly acute myeloblastic but may be acute lymphoblastic or juvenile myeloid in type. It is associated with several trisomies, especially trisomy 21. Trisomy 13, trisomy 1...
Introduction: Langdon Down syndrome (Trisomy 21) is the most common genetic compatible with survival. a chromosomal condition characterized by presence of an additional copy material on chromosome 21, either in full (trisomy or partially, due to translocation. Objective: The importance early detection Down's Syndrome and highlighting complications caused this syndrome. Material methods: In our ...
BACKGROUND In severe congenital neutropenia the maturation of myeloid progenitor cells is arrested. The myelodysplastic syndrome and acute myeloid leukemia develop in some patients with severe congenital neutropenia. Abnormalities in the signal-transduction pathways for granulocyte colony-stimulating factor (G-CSF) may play a part in the progression to acute myeloid leukemia. METHODS We isola...
The treatment of patients with congenital leukemia is difficult and often results in a poor prognosis. We present here the case of a female child with congenital acute myeloid leukemia (AML) with t(8 ; 16) (p11 ; p13) who received chemotherapy and survived for more than 10 years without relapse. A novel MOZ-CBP chimera was found in her diagnostic sample. Although adult AML patients with MOZ-CBP...
Acute lymphoblastic leukemia (ALL) diagnosed in the first month of life (congenital ALL) is very rare. Although congenital ALL is often assumed to be fatal, no studies have been published on outcome except for case reports. The present study reports the outcome of 30 patients with congenital ALL treated with the uniform Interfant-99 protocol, a hybrid regimen combining ALL treatment with elemen...
We report an autopsy case of congenital monoblastic leukemia that developed in monozygotic twins. The twin presented with progressive hepatosplenomegaly at 4 weeks after birth. One twin died of massive bleeding and hypovolemic shock before the treatment started. At autopsy, the liver was diffusely enlarged and showed a diffuse whitish discoloration except for the subcapsular and perivenular are...
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