BACKGROUND This study determined whether dispersion of conduction velocity, refractoriness, or excitability increases biphasic shock defibrillation energy requirements (DERs). METHODS AND RESULTS Twenty-four swine were instrumented with a mid-LAD perfusion catheter for regional infusion of lidocaine 0.75 mg. kg(-1). h(-1) (n=7), low-dose d-sotalol (0.16 mg. kg(-1). h(-1)) (n=4), high-dose d-s...

objective(s):in this study, we aimed at evaluation of electrophysiological and histopathalogical characteristics of statin-induced muscle injury as well as clinical features of patients who develop this condition in terms of frequency and pattern of evolution. materials and methods: forty patients (age 39-74 years) including 25 subjects with type 2 diabetes mellitus, 9 with cardiovascular disea...

Moosa, A., and Dubowitz, V. (1971). Archives of Disease in Childhood, 46, 852. Slow nerve conduction velocity in cretins. The ulnar and posterior tibial conduction velocities were measured in 6 untreated and 3 treated cretins. In 4 of the untreated patients, the conduction velocity of both nerves was slower than normal; in 1 patient the ulnar and in the other the posterior tibial nerve conducti...

Thin sections of canine right and left ventricular endocardium and myocardium were studied in a tissue bath to compare conduction properties of intraventricular specialized conducting tissue [Purkinje fibers (PF)], the superficial layers of subendocardial ventricular muscle (SVM), and the deeper ventricular muscle (DVM) below this level. The study was carried out because of observations that so...

Copyright © 1989 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online ISSN: TX 72514 Circulation Research is published by the American Heart Association. 7272 Greenville Avenue, Dallas, 1989;65;1485-1498 Circ. Res. S Nattel and W Jing inward current and conduction velocity in anesthetized dogs. A quantitative analysis based on the relation between phase 0 Rate-dependen...

MORTIMER, J. THOMAS, ROBERT MAGNUSSON, AND INGEMAR PETERSON. Conduction velocity in ischemic muscle: effect or2 EMG frequency spectrum. Am. J. Physiol. 219(5): 1324-1329. 1970.-The action-potential conduction velocity in Yed” and “white” muscles was studied. The study was made by recording the conduction times during and following periods of repeated contractions while the muscle was ischemic o...

change in transmitting time of impulses along axons is traditionally attributed to two parameters: the myelin formation and the diameter of neurite, both rising during the postnatal development. in the previous study, we showed that conduction velocity of the fibers projecting from the thalamus to the layer iv of the somatosensory (barrel) cortex increases as a function of age. however, the con...

Though peripheral conduction velocity is widely used to characterize afferent fibers according to somatosensory modality, disagreement exists as to whether or not conduction velocity varies along such an axon's length. Therefore, in this experiment, conduction velocities were measured over very short axonal segments (7.5 to 15 mm) within the posterior tibia1 nerve, sciatic nerve, and L7 dorsal ...

INTRODUCTION Nerve conduction velocity slows and amplitude declines with aging. METHODS Median and ulnar sensory nerves were tested at the annual meetings of the American Dental Association. Seven hundred four subjects had at least two observations. The rate of change in the nerve parameters was estimated while controlling for gender, age, change in hand temperature, baseline body mass index ...