Skin is the most extended organ in human body representing 16% of total weight with a surface extension up to 2 m2. From mechanical viewpoint, skin can be described by an hyperelastic membrane, particularly when computational modeling for insilico testing reconstructive surgery procedures needed. These often involves complex topological manipulations tissue order minimize post-operative scarrin...

A quantitative assessment of uncertainties in load, geometrical and material properties by using probabilistic and stochastic analysis is discussed. This allows a rational determination of the propagation of uncertainties through structural systems and ultimately reliability assessment.

The Mycobacterium tuberculosis bacilli's potency to cause persistent latent infection that is unresponsive to the current cocktail of TB drugs is strongly associated with its ability to adapt to changing intracellular environments, and tolerating, evading and subverting host defence mechanisms. We applied a combination of bioinformatics and mathematical modelling methods to enhance the understa...

This paper is concerned with the numerical evaluation of multi-echelon production systems. Each stage requires a fixed predetermined leadtime; furthermore, we assume a stochastic, stauonary eLd.tlmc demand process. In a previous paper, we have developed an analytical framework for determining optimal control pohclcs for such systems under an average COSt criterion The current paper Is based on ...

Computational simulation can be defined as any computer application which involves the numerical solution to a system of partial differential equations. In this paper, a broad overview is given of verification procedures for computational simulation. The two aspects of verification examined are code verification and solution verification. Code verification is a set of procedures developed to fi...

Modern business environment focuses on improving the operational efficiency of supplier, retailer and customers through integrating their inventory. Although a smoothly running integrated inventory system is ideal, the reality is to deal with imperfectness in transportation. In actual production environments, inventory items are not perfect and defectiveness occurs in random process.  In this p...

The estimation of project completion time is to be repeated several times in the project planning phase to reach the optimal tradeoff between time, cost, and quality. Estimation procedures provide either an interval or a point estimate. The computational load of several estimation procedures is reviewed. A multiple polynomial regression model is provided for major interval estimation procedures...