colorectal cancer is an emerging public health problem in indonesia and currently ranks among the three highest cancers. lack of a colonoscopy screening and lifestyle changes might contribute to it. in the last few decades, there is an increasing interest towards the contribution of genetic-environment interaction in colorectal carcinogenesis. some studies have indicated that crc might develop ...

background: colorectal cancer (crc) is the third most common malignancy in iran. limited data are available on knowledge and barriers in regard to crc and screening tests in iran. the aim of  the study was to characterize knowledge, practice, and barriers toward crc and its screening tests among an iranian at‑risk population. methods: this cross‑sectional study was conducted with participation ...

background: today, cancer is one of the major health problems worldwide, and the importance of this disease in our country is growing. this cancer is the third cause of death and accounts for the second largest group of non-transmissible chronic diseases. colorectal cancer is the most common gastrointestinal cancer and includes 10%  of deaths from cancer around the world. different genetic and ...

background: vascular endothelial growth factor (vegf) is a signal protein produced by cells that stimulates angiogenesis and increased vascular permeability. the prognostic value of vegf expression in colorectal cancer is unclear as shown by the discordant results still reported in the literature. this study was designed for the evaluation of vegf expression and correlation with clinicopatholog...

background colorectal cancer (crc) is the second most common malignancy in the world.  however, its mortality rate can be reduced if diagnosed early. p33 ing1b is a tumor suppressor protein, which plays a role in growth control and apoptosis. suppression of p33 ing1b is associated with the loss of cellular growth control. however, p33 ing1b expression in crc and its correlations with clinicopat...

background: improvement in complications of antitumor agents and surgery is important to enhance life quality and survival among patients with colon and colorectal cancer. it has been reported that some dietary components such as glutamine (gln) have beneficial effects on these complications of cancer therapies. however, the results of studies are inconsistent in this area. we performed a revie...

Metastatic ovarian cancers occur in 3-8 percent of women undergoing surgical resection of a primary colorectal cancer. In this study we examined the characteristics of women with colorectal cancer for whom synchronous oophorectomy had been performed. In this cross-sectional study, records of patients with colorectal cancer from April 1991 through October 1999 who had undergone surgery for ...

Adipocytokines, hormones secreted from adipose tissue, have been shown to be associated with many cancers such as breast, prostate and colorectal cancer. Recent studies have indicated that resistin and visfatin, two of these adipokines have high level plasma concentrations in colorectal cancer patients and may be promising biomarkers for colorectal cancer. The aim of this study was to identify ...

aim : the aim of this study was to report the anatomical location and histologic type of colorectal polyps in a large series of iranian patients that attended for colonoscopy. background : polyps that develop through the adenoma-carcinoma pathway are considered neoplastic and may eventually progress to invasive carcinomas. in addition polyps can develop with no neoplastic potential. these neopl...