Colorectal cancer often arises from adenomatous colonic polyps. Polyps can grow and progress to cancer, but may also remain static in size, regress, or resolve. Predicting which polyps progress and which remain benign is difficult. We developed a novel long-lived murine model of colorectal cancer with tumors that can be followed by colonoscopy. Our aim was to assess whether these tumors have si...

Dietary folate appears to be inversely related to colorectal cancer risk. This study investigated the effects of dietary intervention with folate or the development of intestinal polyps in Min (Apc +/-) mice. Weanling Mil mice were fed diets containing 0, 2 (basal requirement), 8, or 20 mg folate/kg diet. At 3 and 6 months of dietary intervention, 50% of the mice from each group were sacrificed...

background: routine screening colonoscopy is on the rise and pathologists have to deal with the ever larger numbers of excised colonic polyps. it is very important to optimize the patients’ individual treatment and further surveillance. pathologists play a critical role in management, as most of the clinical decisions concerning colonic polyp management are based on pathologic findings. one of ...

BACKGROUND Fundic gland polyps (FGPs) of the stomach were originally described in association with familial polyposis syndromes. It is now known that the majority of these polyps occur in the sporadic setting and are incidentally seen in up to 1.9% of routine upper gastrointestinal endoscopes. The aim of this study was to look at the clinico-pathological features of the FGPs and to analyse thei...

PURPOSE Endoscopic treatment of sessile and semipedunculated polyps remains controversial. Residual tissue remains frequently after endoscopic snare polypectomy. The aim of the study was to assess the outcome and safety of argon plasma coagulation (APC) in the management of gastric and colorectal polyp remnants after polypectomy, and to search for clinical parameters useful in predicting the ef...

The nuclei of colonic adenomatous polyps and some colonic carcinomas have a normal diploid profile. The remaining carcinomas are aneuploid, and this change most probably occurs after the dysplasia that determines invasiveness, because even adenomatous polyps with carcinoma in situ are diploid.

W. Ajaj, N. Papanikolaou, J. F. Debatin, T. Lauenstein, S. G. Ruehm University Hospital Essen, 45122 Essen, NRW, Germany, Department of Radiology, Crete, Crete, Greece ABSTRACT: The aim of this study was to assess MR colonography for the detection of colonic polyps/malignancy. 50 subjects underwent MR colonography prior to conventional colonoscopy. MRC is based on a rectal enema with water in c...

Colorectal carcinoma ranks third in frequency among all cancers. With regards to cancer related mortality, colorectal carcinoma is known as the second cause (Levin et al., 2003). This condition accounts for 10% of all cancer related mortalities in women and men. Overall, lifetime risk for the development of colorectal carcinoma is still 5%. (Eddy, 1990) The wellknown risk factors are age, inher...

OBJECTIVE To determine the effect of reduced abdominal compression in prone position on ascending colonic movement during supine-to-prone positional change during CT colonography (CTC). MATERIALS AND METHODS Eighteen consecutive patients who had undergone prone CTC scanning with cushion blocks placed under the chest and hip/thigh to reduce abdominal compression and had confirmed sessile polyp...

background geographic information system (gis) software has been used in health care systems to display and analyze spatial pattern of diseases and health services. objectives this study was performed to assess spatial patterns of colon’s pathologic lesions based on the pathologic reports and assess whether it is possible to use gis software in health services. patients and methods archives of ...