نتایج جستجو برای: colon cancers
تعداد نتایج: 159069 فیلتر نتایج به سال:
most patients with gastrointestinal cancers refer to the health centers at advanced stages of the disease and conventional treatments are not significantly effective for these patients. therefore, using modern therapeutic approaches with lower toxicity bring higher chance for successful treatment and reduced adverse effects in such patients. the aim of this study is to evaluate the effect of av...
BACKGROUND We evaluated the clinicopathologic features and outcomes of Taiwanese patients with right-sided versus left-sided colon cancer according to various cancer stages. METHODS A total of 1095 patients with primary colorectal cancer (CRC) undergoing surgery at a single-institution were enrolled. We analyzed patient differences in terms of clinicopathologic features, overall survival (OS)...
BACKGROUND Incidence rates of colorectal cancer (CRC) in New Zealand rank among the highest worldwide. Internationally, there has been evidence of a shift in colon cancer from left- to right-sided. The objective of this study was to determine trends in left- and right-sided colon and rectal cancers incidence by sex, age and ethnicity. METHODS Using datasets created by linking data from the Ne...
OBJECTIVE This study was to explore the expression of human cervical cancer oncogene-1 (HCCR-1) in colon cancer and its clinical significance. METHODS RT-PCR, immunohistochemistry and Western blot assay were employed to detect HCCR-1 expression in 152 colon cancers, 43 adjacent non-cancerous tissues and 37 normal tissues. In addition, immunohistochemistry was done to detect CEA in colon cance...
Observations support the theory that development of left- and right-sided colorectal cancers may involve different mechanisms. This study investigated different genes involved in oncogenesis of colon and rectal cancers and analysed their prognostic value. The study group comprised 35 colon and 42 rectal cancers. Rectal cancer patients had been treated with standardized surgery performed by an e...
introduction: prostatic specific antigen (psa) is an important tumor marker of prostatic cancer and antigenic determinant of prostatic tissue. however, recently, results of several researches have proposed existence of psa in non- prostatic tumors, extracts . in this study, our goal was to find that if patients with non-prostatic cancers synthesize psa. materials & methods : the sample was sel...
We are pleased to read the letter by Ashktorab et al. (1). We agree with Ashktorab et al. on the need for additional whole-exome sequencing of colon cancers arising in African Americans and on the value of continuing to add more cases to the numbers of African American colon cancers that have been characterized. The additional 11 African American colon cancers reported by Ashktorab et al. will ...
BACKGROUND Activin receptor 2 (ACVR2) is commonly mutated in microsatellite unstable (MSI) colon cancers, leading to protein loss, signaling disruption, and larger tumors. Here, we examined activin signaling disruption in microsatellite stable (MSS) colon cancers. METHODS Fifty-one population-based MSS colon cancers were assessed for ACVR1, ACVR2 and pSMAD2 protein. Consensus mutation-prone p...
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