نتایج جستجو برای: collagen type i
تعداد نتایج: 2253406 فیلتر نتایج به سال:
objective(s):skin extracellular matrix, which contains type i and type iii collagens, is involved in skin development. the aim of this study was to investigate type iii collagen distribution pattern as well as its changes during pre and post-natal skin morphogenesis in rats. materials and methods: ventral skins of wistar rat embryos at different stages from 10 to 20 gestational day (e10-e20) an...
Purpose: Effects of TGF-b and b-FGF on the Potential of Peripheral Blood-Borne Stem Cells and Bone Marrow-Derived Stem Cells In Wound Healing in a Murine Model.Materials and Methods: Peripheral blood mesenchymal stem cells (PBMSCs) and bone marrow stem cells (BMSCs) cultured in media with transforming growth factor-beta (TGF-b) and basic fibroblast growth factor (b-FGF). Stem cells labeled with...
Background: With the aim of regenerating healthy tissues, different tissue engineering strategies pointed to extracellular matrix (ECM)-based scaffolds in tissue engineering and regenerative medicine and wound healing. It is a multidisciplinary science works to create biocompatible scaffolds with perfect physical parameters, mechanical integrity and high porosity to promote cell growth, migrati...
Type I collagen is the predominant collagen in mature tendons and ligaments, where it gives them their load-bearing mechanical properties. Fibrils of type I collagen are formed by the packing of polypeptide triple helices. Higher-order structures like fibril bundles and fibers are assembled from fibrils in the presence of other collagenous molecules and noncollagenous molecules. Curiously, howe...
In the present study, we demonstrate delayed-type hypersensitivity (DTH) to homologous type I collagen that cross-reacts with type IV collagen. Mice immunized with native or denatured type I collagens and challenged with these same antigens or native type IV collagen develop a peak DTH response on day 7. Challenge with denatured type IV collagen or collagenase-treated type IV collagen failed to...
background: osteoarthritis is one of the most common diseases in middle‑aged populations in the world and could become the fourth principal cause of disability by the year 2020. one of the critical properties for cartilage tissue engineering (te) is the ability of scaffolds to closely mimic the extracellular matrix and bond to the host tissue. therefore, te has been presented as a technique to ...
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