نتایج جستجو برای: cognitiveimpairment cranial irradiation

تعداد نتایج: 89231  

Journal: :iranian red crescent medical journal 0
minas sakellakis division of oncology, department of medicine, university hospital, patras medical school, university of patras, rion 26504, patras, greece; division of oncology, department of medicine, university hospital of patras, rion 26504, greece. tel: +30-2610999535, fax: +30-2610994645 stavros peroukides division of oncology, department of medicine, university hospital, patras medical school, university of patras, rion 26504, patras, greece gregoris iconomou division of oncology, department of medicine, university hospital, patras medical school, university of patras, rion 26504, patras, greece haralabos kalofonos division of oncology, department of medicine, university hospital, patras medical school, university of patras, rion 26504, patras, greece

conclusions physicians should be aware of this rare site of metastasis. early diagnosis is of paramount importance in order to effectively prevent the significant morbidity this condition can cause if left untreated. introduction small cell carcinoma constitutes the most aggressive type of lung cancer, with the greatest propensity for early disseminated disease. although commonly neglected due ...

Journal: :Radiation Oncology (London, England) 2008
Franziska Eckert Arndt-Christian Müller

In extensive disease of small cell lung cancer a doubling of the one-year-survival rate was reported in August 2007 by prophylactic cranial irradiation applied to patients who experienced any response to initial chemotherapy. We discuss the treatment concept of extensive disease in the face of the latest results and older studies with additional thoracic irradiation in this subgroup. A randomiz...

Journal: :Postgraduate medical journal 1988
H S Pall S Nightingale C G Clough D Spooner

A 38 year old woman who had undergone irradiation during infancy for a left facial cutaneous arteriovenous malformation sequentially developed complete palsies of the ipsilateral VII, V, XI, IX, X, XII and VI cranial nerves. Apart from optic and olfactory nerve damage there are few reports of radiotherapy causing cranial nerve injury. We link the unusually extensive and progressive neural damag...

Journal: :British medical journal 1973
J E Freeman P G Johnston J M Voke

A transient cerebral disturbance characterized by somnolence of varying degree is described in children after cranial irradiation given as part of central nervous system (C.N.S.) prophylaxis for acute lymphoblastic leukaemia in remission.Out of 28 such children receiving cranial irradiation as part of the Medical Research Council protocol for C.N.S. prophylaxis 11 (39%) developed pronounced sym...

Journal: :Haematology and blood transfusion 1981
L F Sinks J J Wang A I Freeman

Fifty-four consecutive children with acute lymphocytic leukemia (ALL) were treated from August 1974 until December of 1976 at Rosewell Park Memorial Institute (RPMI) according to a protocol which substituted cranial irradiation with systemic intermediate dose methotrexate (IDM) 500 mg/m2 each 3 weeks for a total of 3 courses immediately following induction. Of 54 patients, 52 went into remissio...

Journal: :The New England journal of medicine 1986
D A Laber

The role of radiation therapy in the primary management of small cell lung cancer is very much a matter of current debate. Its value in palliative treatment is unquestioned. Disappointment in the apparent inability to demonstrate improvement in survival in some randomized studies as a result of locoregional radiotherapy and prophylactic cranial irradiation may be due to the use of inappropriate...

Journal: :Cancer 2006
James G Gurney Kirsten K Ness Shalamar D Sibley Maura O'Leary Donald R Dengel Joyce M Lee Nancy M Youngren Stephen P Glasser K Scott Baker

BACKGROUND The purpose of the study was to determine the prevalence of metabolic syndrome, growth hormone deficiency, and cardiovascular risk factors among adult survivors of childhood acute lymphoblastic leukemia (ALL) treated with or without cranial irradiation. METHODS Follow-up was undertaken of 75 randomly selected long-term childhood ALL survivors. Testing included fasting insulin, gluc...

Journal: :Hematology. American Society of Hematology. Education Program 1993
Ching-Hon Pui

Improved treatment for acute lymphoblastic leukemia (ALL) has virtually eliminated testicular relapse. However, the control of central nervous system (CNS) leukemia remains a therapeutic challenge in childhood ALL, partly because of the late complications arising from cranial irradiation. In most current pediatric protocols, cranial irradiation (12 to 18 Gy) is given to 5% to 25% of patients--t...

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