نتایج جستجو برای: cmax

تعداد نتایج: 3755  

Journal: :The Journal of pharmacology and experimental therapeutics 2003
Michael W Konstan Jeanne E Krenicky Marcie R Finney H Lester Kirchner Kathleen A Hilliard Jay B Hilliard Pamela B Davis Charles L Hoppel

Long-term treatment with ibuprofen twice daily, at doses that achieve peak plasma concentration (Cmax) >50 microg/ml, slows progression of lung disease in patients with cystic fibrosis (CF). Previous data suggest that Cmax >50 microg/ml is associated with a reduction in neutrophil (PMN) migration into the lung and that lower concentrations are associated with an increase in PMN migration. To es...

2017
Lin Chen Dániel Marx Deshi Ye Guochuan Zhang

We study approximation and parameterized algorithms for R||Cmax, focusing on the problem when the rank of the matrix formed by job processing times is small. Bhaskara et al. [2] initiated the study of approximation algorithms with respect to the rank, showing that R||Cmax admits a QPTAS (Quasi-polynomial time approximation scheme) when the rank is 2, and becomes APX-hard when the rank is 4. We ...

Journal: :VNU Journal of Science: Medical and Pharmaceutical Sciences 2022

Abstract: We conducted this research to determine the NAT2 gene-phenotype characteristics and pharmacokinetics (PK) parameters of isoniazid among patients with non-MDR pulmonary tuberculosis. Data were collected from 132 diagnosed newly acquired or relapsed tuberculosis treated at 03 hospitals: Hanoi Lung Hospital, Central National K74 Hospital. PK samples one day 10th – 14th after commencing t...

2017
Jana Leshinsky Andrew McLachlan David J R Foster Ross Norris Vanessa R Barrs

Cats are the most common mammal to develop invasive fungal rhinosinusitis caused by cryptic species in Aspergillus section Fumigati that are resistant to azoles but susceptible to caspofungin. In this study nonlinear mixed-effects pharmacokinetic modeling and simulation was used to investigate caspofungin pharmacokinetics and explore dosing regimens in cats using caspofungin minimum effective c...

Journal: :Journal of experimental botany 2005
Yusuke Onoda Kouki Hikosaka Tadaki Hirose

The balance between the capacities of RuBP (ribulose-1,5-bisphosphate) carboxylation (V(cmax)) and RuBP regeneration (expressed as the maximum electron transport rate, J(max)) determines the CO(2) dependence of the photosynthetic rate. As it has been suggested that this balance changes depending on the growth temperature, the hypothesis that the seasonal change in air temperature affects the ba...

Journal: :Applied optics 2006
Roland J Leigh Gary K Corlett Udo Friess Paul S Monks

The development of a new concurrent multiaxis (CMAX) sky viewing spectrometer to monitor rapidly changing urban concentrations of nitrogen dioxide is detailed. The CMAX differential optical absorption spectroscopy (DOAS) technique involves simultaneous spectral imaging of the zenith and off-axis measurements of spatially resolved scattered sunlight. Trace-gas amounts are retrieved from the meas...

Journal: :European journal of pharmacology 2011
Rie Ikeda Yoshiko Igari Yuki Fuchigami Mitsuhiro Wada Naotaka Kuroda Kenichiro Nakashima

3,4-methylenedioxymethamphetamine (MDMA) is a psychoactive stimulant abused by young people as the recreational drug ecstasy. Other compounds, either deliberately added or present as byproducts, are often found in MDMA tablets and can unexpectedly interact with each other. The aim of this study was to evaluate the pharmacodynamic effects of interactions caused by concomitants in MDMA tablets on...

2013
Mona Rafik Loutfy Sharon Lynn Walmsley Marina Barbara Klein Janet Raboud Alice Lin-in Tseng Sandra Lauren Blitz Neora Pick Brian Conway Jonathan Benjamin Angel Anita Rochelle Rachlis Kevin Gough Jeff Cohen David Haase David Burdge Fiona Mary Smaill Alexandra de Pokomandy Hugues Loemba Sylvie Trottier Charles Jean la Porte

BACKGROUND Although some studies show higher antiretroviral concentrations in women compared to men, data are limited. We conducted a cross-sectional study of HIV-positive women to determine if protease inhibitor (PI) and non-nucleoside reverse transcriptase inhibitor (NNRTI) C(min) and Cmax values were significantly different than historical general population (predominantly male) averages and...

Journal: :Limnology and Oceanography 2023

In sunlit waters, significant predation is performed by unicellular, phagotrophic mixotrophs, that is, predators also possess plastids. The success of a mixotrophic lifestyle will depend in part on how well mixotrophs acquire prey relative to specialized heterotrophs. Likewise, consequences mixotrophy for productivity and element cycling the rate efficiency at which consume biomass However, tra...

2013
Fatima M. Osman Saleh H. Al-Sharaeh

In the last few years, a significant increasing interest in the Wireless Sensor Networks (WSN) is noticed. A great challenge in WSN is the limitation of power in sensor nodes batteries, hence developing energy efficient solutions is a key issue for prolonging the lifetime of these networks. CMAX and OML are power efficient routing heuristics that have been proposed to maximize sensor networks l...

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