Clothianidin was given in the diet to provide levels of 0% (control), 0.003%, 0.006%, and 0.012% from 5 weeks of age of the F(0) generation to 11 weeks of age of the F(1) generation in mice. Selected reproductive and neurobehavioral parameters were measured. In exploratory behavior in the F(0) generation, average time of movement, number of rearing, and rearing time of adult males increased ...

Numerous studies have documented the negative effects of neonicotinoids on bees; it remains crucial to examine how affect other non-target nectar-feeding insects, such as monarch butterfly, Danaus plexippus. Wildflowers growing near agricultural areas can be contaminated with that survival or cause sublethal changes behaviours insects. Nectar residues imidacloprid and clothianidin found in milk...

Western corn rootworm, Diabrotica virgifera virgifera LeConte, neonate susceptibility to clothianidin, a contact and systemic neonicotinoid insecticide, was determined from both laboratory and field-collected populations. Neonates were exposed to filter paper treated with increasing clothianidin concentrations and mortality was evaluated after 24 h. Additionally, two populations were exposed to...

Neonicotinoid seed treatments, typically clothianidin or thiamethoxam, are routinely applied to >80% of maize (corn) seed grown in North America where they are marketed as a targeted pesticide delivery system. Despite this widespread use, the amount of compound translocated into plant tissue from the initial seed treatment to provide protection has not been reported. Our two year field study co...

Neonicotinoid insecticides are widely used to protect plants against pest insects, and insecticide residues remaining in the environment affect both target and non-target organisms. Whereas low doses of neonicotinoids have been shown to disturb the behaviour of pollinating insects, recent studies have revealed that a low dose of the neonicotinoid clothianidin can improve behavioural and neurona...

Insect species richness and abundance has declined rapidly over the last few decades. Various stressors, such as conversion of natural habitats, climate change, land-use intensification, agrochemicals pathogens, are thought to be major factors in this decline. We treated female bees two common pollinator Europe, Osmia bicornis Bombus terrestris , with a field-realistic dose neonicotinoid clothi...

Neonicotinoids currently dominate the insecticide market as seed treatments on Canada's major Prairie crops (e.g., canola). The potential impact to ecologically significant wetlands in this dominantly agro-environment has largely been overlooked while the distribution of use, incidence and level of contamination remains unreported. We modelled the spatial distribution of neonicotinoid use acros...

Management of onion maggot, Delia antiqua (Meigen), in onion requires the use of an insecticide applied at planting. Insecticide resistance and a dearth of available products have stimulated an effort to identify new insecticides for onion maggot control, especially chemistries that can be delivered as seed treatments. Onion seeds film-coated with fipronil, spinosad, clothianidin or thiamethoxa...

Neonicotinoid pesticides have been widely applied for the production of fruits and vegetables, and occasionally detected in conventionally grown produce. Thus oral exposure to neonicotinoid pesticides may exist in the general population; however, neonicotinoid metabolites in human body fluids have not been investigated comprehensively. The purpose of this study is the qualitative profiling and ...

Pollinators in agricultural landscapes can be exposed to mixtures of pesticides and environmental pollutants. Existing mixture toxicity modelling approaches, such as the models of concentration addition and independent action and the mechanistic DEBtox framework have been previously shown as valuable tools for understanding and ultimately predicting joint toxicity. Here we apply these mixture m...