BACKGROUND Mycobacterium tuberculosis complex species display relatively static genomes and 99.9% nucleotide sequence identity. Studying the evolutionary history of such monomorphic bacteria is a difficult and challenging task. PRINCIPAL FINDINGS We found that single-nucleotide polymorphism (SNP) analysis of DNA repair, recombination and replication (3R) genes in a comprehensive selection of ...

Tylophora indica Burm F. Merrill. is widely used against various diseases owing to the presence an array of medicinally important secondary metabolites. Its stem is bitter, stomachic, stimulates bile secretion, enriches the blood and cures diseases like diabetes, fever, flatulence, hypertension, jaundice, leucorrhoea, urinary disease and upper respiratory tract infection. It is neglected for ti...

to improve commercial grapevine cultivars, it is necessary to apply such methods that by cultivation of a certain number of vines in a certain area, higher yield could be harvested. to achieve such a goal, healthy stocks with resistant to pests and diseases, high fructification and high quality of vines are needed. all these properties can be obtained successfully through clonal selection. viti...

Dendrocalamus strictus popularly known as 'Male bamboo' is a multipurpose bamboo which is extensively utilized in pharmaceutical, paper, agricultural and other industrial implements. In this study, in vitro regeneration of D. strictus through nodal culture has been attempted. Murashige and Skoog's medium supplemented with 4 mg/l BAP was found to be most effective in shoot regeneration with 3.68...

Introduction: This paper details an evaluation of the implementation and feasibility of a multilevel project entitled Kin KeeperSM Cancer Prevention Intervention that utilizes community health workers (CHWs) to deliver breast and cervical cancer education. The evaluation includes intervention fidelity, participant satisfaction, participant retention, and the cost of program implementa...

the integration of an approximate model and a clonal selection algorithm (csa) is considered to one of the most effective ways to solve complex optimization design problems in engineering. in this study, first, a process for developing an approximate model and the principles of clonal selection algorithms were presented. then, a variotherm temperature injection mold used to produce a large liqu...

toxoplasma gondii is one of the most prevalent parasitic infections in world. rh, ned and me49 are of the most prevalent clonal types of the parasite isolated till now. differences in pathogenicity and virulence of different types have been investigated in different studies. no controlled study was performed to compare the ability of different types to initiate humoral immune response. we inves...