Discussion: A large part of both clinical and subclinical lesions found in our daily work are benign and correspond with fibrocystic changes (FCC). This entity is complex and part exhibit traits that define characteristically in MRI and diagnose correctly, but there is another small group of changes that can take the image aspect of cancer. From a complex case, we review the main aspects of the...

Background: Cancer stem cells (CSCs) are a group of tumor cells with self-renewal property and differentiation potential. CSCs play a crucial role in malignant progression of several types of tumors. However, what is still controversial is the clinicopathological relationship between Nanog marker and its prognostic value in the patients with breast cancer. The expression of Nanog in the patient...

BACKGROUND AND AIM Centrilobular zonal necrosis (CZN) is a known histological variant of autoimmune hepatitis (AIH). However, the significance of CZN is yet to be fully elucidated. This study aimed to determine whether CZN is a hallmark of a distinctive subtype of AIH. METHODS Histological changes in the centrilobular zones of liver biopsies from 113 AIH patients were assessed by a single pat...

Cognitive abilities rise steeply from infancy to young adulthood and then are either maintained or decline to old age, depending on the specific ability. This pattern suggests corresponding continuities of mechanism and process, but it is striking that the fields of cognitive development and cognitive aging make little contact with each other's methods and theories. In this review we examine re...