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Quantitative analysis of clinical language samples is a powerful tool for assessing and screening developmental language impairments, but requires extensive manual transcription, annotation, and calculation, resulting in error-prone results and clinical underutilization. We describe a system that performs automated morphological analysis needed to calculate statistics such as the mean length of...

INTRODUCTION microRNAs (miRNAs) are considered to be novel molecular biomakers that could be exploited in the diagnosis and treatment of different diseases. The present study aimed to develop an efficient miRNA isolation method from different clinical specimens. METHODS Total RNAs were isolated by Trizol reagent followed by precipitation of the large RNAs with potassium acetate (KCH3COOH), po...

The Infinium Human Methylation450 BeadChip Array (TM) (Infinium 450K) is an important tool for studying epigenetic patterns associated with disease. This array offers a high-throughput, low cost alternative to more comprehensive sequencing-based methodologies. Here we compare data generated by interrogation of the same seven clinical samples by Infinium 450K and reduced representation bisulfit...