few biomarkers that can predict the clinical response to allergen immunotherapy (ait) have been identified. the aim of the present study was to investigate parameters that could be used “in predicting the clinical response to ait” in children with asthma caused by house dust mites. we evaluated 107 children with mild persistent asthma who were sensitised only to mite aeroallergens. the study gr...

Background: Intrauterine infections (TORCH) lead to the involvement of various organs of the body of the fetus, including the eye. The aim of this study was to determine the frequency and clinical response of eye lesions to specific drugs, in infants with confirmed TORCH induced ocular lesions. Methods: This historical cohort study from 2011 to 2017, had done in Pediatrics and Ophthalmology De...

Background: Basal Cell Carcinoma (BCC) is the most common type of skin cancer in human beings. Photodynamic therapy (PDT) is a novel therapeutic method which may be regarded as a non-invasive useful alternative for traditional treatments of BCC. This study was designed with the aim of evaluating the primary response of BCC to PDT.Methods: This clinical trial was perform...

this study evaluated the effects of mesobuthus eupeus (me) scorpion venom on inflammatory response following injection. additionally, the present study examined whether immunotherapy at specific time intervals would be effective on inflammatory response after me venom inoculation. animals were divided randomly into four groups: the first group received ld50 of venom and the second and third gro...

in this report, the clinical course and treatment response of 210 patients with grawes’ disease referred to the research institute for nuclear medicine were studied. the disease was more common in 3rd and 4th decades and more frequent in women (f/m=4). treatment response with antithyroid drugs was about 50%, whereas 80% of the patients treated by i-131 showed positive response. there was no mea...

In this report, the clinical course and treatment response of 210 patients with Grawes’ disease referred to the research institute for nuclear medicine were studied. The disease was more common in 3rd and 4th decades and more frequent in women (F/M=4). Treatment response with antithyroid drugs was about 50%, whereas 80% of the patients treated by I-131 showed positive response. There was ...

the purpose of this study was to describe the feasibility of a combined preoperative chemoradiation program ib-iia, bulky and suspicious iib by radical surgery in patients with stage ib-iib cervical cancer. from september 1999 to april 2002, 30 patients with carcinoma of the cervix were treated with preoperative external beam radiotherapy of 45 gy in 5 weeks. patients received concurrent contin...

In this review, we examine studies that use item response theory (IRT) to explore the psychometric properties of clinical measures. Next, we consider how IRT has been used in clinical research for: scale linking, computerized adaptive testing, and differential item functioning analysis. Finally, we consider the scale properties of IRT trait scores. We conclude that there are notable differences...