Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

Tumour markers are biochemical indicators of the presence of a tumour, which are selectively produced by the neoplastic tissue and released into blood or in other body fluids. They are widely accepted and applied to the management of patients with cancer since the introduction of diagnostic immunopathology. Tumour markers include oncofetal antigens (AFP), glycoproteins (CEA), placental proteins...

The subtle differences between normal and tumor cells are exploited in the detection and treatment of cancer. These differences are designated as tumor markers and can be either qualitative or quantitative in their nature. That means that both the structures that are produced by tumor cells as well as the structures that are produced in excessive amounts by host tissues under the influence of t...

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

the investigation and determination of the significance of neovascularization in the progression of soft tissue sarcoma is currently of increasing clinical importance. microvessel density is the morphologic evidence of neoangiogenesis in the process of malignant progression of sarcomata. this brief review of the markers commonly used in clinical practice was undertaken to determine the validity...