Fluids are the only known method of attenuating renal injury. Furthermore, fluid prescriptions whether for hydration, resuscitation or renal replacement therapy, must be tailored to the fluid and electrolyte, cardiovascular status and residual renal function of the patient. Different fluids have significantly different effects both on volume expansion as well as electrolyte and acid-base balanc...

BACKGROUND Epidermal growth factor receptor (EGFR) mutation is strongly associated with the therapeutic effect of tyrosine kinase inhibitors (TKIs) in patients with non-small-cell lung cancer (NSCLC). Nevertheless, tumor tissue that needed for mutation analysis is frequently unavailable. Body fluid was considered to be a feasible substitute for the analysis, but arising problems in clinical pra...

INTRODUCTION  Fluid therapy is one of the cornerstones of initial management of sepsis, but the choice of fluids used for resuscitation is controversial.  OBJECTIVES  While trying to determine the effects of alternative fluids used in sepsis resuscitation randomized controlled trials (RCTs), we found that the precise description of those fluids was frequently not available. This report presen...

Aim: Since the free amino acids (a.a.) and derivated a.a. compounds in physiological fluids might reflect physiological or pathological conditions, some researchers have investigated the correlation of a.a. concentrations in physiological fluids with some clinical conditions, including ocular diseases. Here, we aimed to compare free and derivated a.a. in nuclear (generally a physiologic conditi...

Consecutively collected synovial fluids were examined for presence of bacterial DNA (a 700-bp fragment of the bacterial 23S rRNA gene) followed by DNA sequencing of amplicons, and by conventional bacteriological methods. One or more microorganisms were identified in 22 of the 227 synovial fluids (9,7%) originating from 17 patients. Sixteen of the patients had clinical signs of arthritis. For 11...

Phosphorylation plays a critical role in regulating protein function and thus influences a vast spectrum of cellular processes. With the advent of modern bioanalytical technologies, examination of protein phosphorylation on a global scale has become one of the major research areas. Phosphoproteins are found in biological fluids and interrogation of the phosphoproteome in biological fluids prese...

Some 40% of knee-joint synovial fluids from arthritic patients show the presence of bleomycin-detectable iron. This is released from a protein component of the fluid to bleomycin at acidic pH values. Patients whose fluids release iron have lower contents of transferrin, lactoferrin and caeruloplasmin than do patients whose fluids do not release iron to bleomycin. These proteins are important ex...

OBJECTIVE To evaluate the clinical efficacy of intravenous (IV) fluid warming in patients undergoing laparoscopic colorectal surgery. METHODS Adult patients undergoing laparoscopic colorectal surgery were randomly assigned to receive either IV fluids at room temperature (control group) or warmed IV fluids (warm fluids group). Each patient received a standardized goal-directed fluid regimen ba...

background and objectives: meningoencephalitis in iranian children is frequent, but encephalitis is rare .the frequency of hhv-6 and hhv-7 in central nervous system diseases of our children is unclear. the aim of this study was searching the dna-s of hhv-6 & hhv-7 in csf samples of children with meningoencephalitis  materials and methods: a cross sectional study (2007-2009) was done in ped...