نتایج جستجو برای: circumsporozoite protein

تعداد نتایج: 1234774  

Journal: :The Journal of biological chemistry 2007
Photini Sinnis Alida Coppi Toshihiko Toida Hidenao Toyoda Akiko Kinoshita-Toyoda Jin Xie Melissa M Kemp Robert J Linhardt

Heparan sulfate has been isolated for the first time from the mosquito Anopheles stephensi, a known vector for Plasmodium parasites, the causative agents of malaria. Chondroitin sulfate, but not dermatan sulfate or hyaluronan, was also present in the mosquito. The glycosaminoglycans were isolated, from salivary glands and midguts of the mosquito in quantities sufficient for disaccharide microan...

2012
Stephen A. Kaba Margaret E. McCoy Tais A. P. F. Doll Clara Brando Qin Guo Debleena Dasgupta Yongkun Yang Christian Mittelholzer Roberta Spaccapelo Andrea Crisanti Peter Burkhard David E. Lanar

BACKGROUND The worldwide burden of malaria remains a major public health problem due, in part, to the lack of an effective vaccine against the Plasmodium falciparum parasite. An effective vaccine will most likely require the induction of antigen specific CD8(+) and CD4(+) T-cells as well as long-lasting antibody responses all working in concert to eliminate the infection. We report here the eff...

Journal: :Proceedings of the National Academy of Sciences 2012

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