Essential oils present a fine antibacterial performance against a variety of bacteria. The main component of the cinnamon oil was eugenol (75.52%). In this study, the goal was to evaluate the antimicrobial activity and reveal bactericidal mechanism of cinnamon oil. Firstly, the minimum inhibitory concentration (MIC) and the minimum bactericide concentration (MBC) of cinnamon oil were tested. Th...

Colorectal cancer (CRC) is a major cause of tumor-related morbidity and mortality worldwide. Recent research suggests that pharmacological intervention using dietary factors that activate the redox sensitive Nrf2/Keap1-ARE signaling pathway may represent a promising strategy for chemoprevention of human cancer including CRC. In our search for dietary Nrf2 activators with potential chemopreventi...

While being important for its culinary use, cinnamon is also highly valued for providing significant health benefits [1] including lowering blood sugar levels [2-5], reducing heart disease risk factors [5-7], and even addressing neurological disorders [8-10]. High levels of antioxidants are in present in cinnamon and likely contribute to these health benefits. Cinnamon is made from the dried in...

BACKGROUND In order to detect the antimicrobial mechanism of combined treatment of cinnamon oil and gamma irradiation (GI), the membrane fatty acids and proteins characteristics of Shewanella putrefaciens (S. putrefaciens) treated with cinnamon oil and GI, and the distribution of cinnamon oil in S. putrefaciens were observed in this study. RESULTS The membrane lipid profile of S. putrefaciens...

OBJECTIVES Treatment of diabetic subjects with cinnamon demonstrated an improvement in blood glucose concentrations and insulin sensitivity but the underlying mechanisms remained unclear. This work intends to elucidate the impact of cinnamon effects on the brain by using isolated astrocytes, and an obese and diabetic mouse model. METHODS Cinnamon components (eugenol, cinnamaldehyde) were adde...

Background: Cinnamon has been shown to potentiate the hypoglycaemic effect of insulin through up regulation of the glucose uptake in cultured adipocytes of rats. This study tried to find out the effect of Cinnamon alone or in combination with Insulin in diabetic albino rats. Methods: Thirty rats were divided into three groups, A and B. Group A were given cinnamon extract 200 mg/Kg body weight d...

recent article in Pediatrics warns against inhaling cinnamon powder and cites experiments that demonstrated chronic inflammation and fibrotic changes to the pulmonary tissue of rats forced to inhale cinnamon powder, and was written in response to the growing popularity of the cinnamon challenge.1 The cinnamon challenge has existed for nearly a decade.2 This dare consists of consuming one tables...

Naturally-occurring compounds that have been shown to improve insulin sensitivity include Cr and polyphenols found in cinnamon (Cinnamomon cassia). These compounds also have similar effects on insulin signalling and glucose control. The signs of Cr deficiency are similar to those for the metabolic syndrome and supplemental Cr has been shown to improve all these signs in human subjects. In a dou...