OBJECTIVE The association of chlorhexidine (CHX) and sodium hypochlorite (NaOCl) to enhance their chemical properties during root canal biomechanical preparation can lead to a brown flocculate being formed. Therefore, this study evaluated the metals present in their association by atomic absorption spectrophotometry, and evaluated a possible reagent that could dissolve the flocculate, allowing ...

Fiber meshes of poly(hydroxybutyrate) (PHB) and poly(hydroxybutyrate)/ poly(ethylene oxide) (PHB/PEO) with different concentrations of chlorhexidine (CHX) were prepared by electrospinning, for assessment as a polymer based drug delivery system. The electrospun fibers were characterized at morphological, molecular and mechanical levels. The bactericidal potential of PHB and PHB/PEO electrospun f...

Short title: Biofilm resistance to chlorhexidine ¤ These authors contributed equally to this work. Abstract We combined experiments and mathematical modeling to study the recovery of oral multispecies biofilms following antimicrobial treatment, and further utilized mathematical modelling to explore the dynamics of the tolerance mechanisms of biofilms. Specifically, we investigated the proportio...

The effect of cycloheximide (CHX; 5 mg/kg) on proenkephalin (proENK) and tyrosine hydroxylase (TH) mRNA expression in rat central and peripheral nervous systems was studied. CHX increased proENK and TH mRNA levels in the adrenal gland, but not in hippocampus, striatum, midbrain, brainstem, pituitary, and hypothalamus. The pretreatment with actinomycin D (0.5 mg/kg) significantly decreased CHX-i...

Aim: To compare the antimicrobial capacity of Chlorine Dioxide (ClO2), Sodium Hypochlorite (NaOCl) and Chlorhexidine (CHX) in microorganisms isolated from persistent apical periodontitis ATCC strains. Materials methods: The included were analyzed by Minimum Inhibitory Concentration (MIC): 50 µl saline solution 100 0.25%, 1% 2% used to make following dilutions 1:2, 1:4, 1:8, 1:16, 1:32, 1:64, 1:...

AIM: The study was done to assess the antimicrobial effectiveness of Chitosan Nanoparticles (CNPs), Chlorhexidine (CHX), and their combination (CHX/CNPs) versus that Sodium hypochlorite (NaOCl) in patients with mandibular necrotic premolars evaluate effects on post-operative pain after single-visit endodontic treatment. MATERIALS AND METHODS: Sixty were divided randomly four groups (n = 15) acc...

background: chlorhexidine (chx) as a gold standard chemical agent appears to be the most effective antimicrobial agent for reduction of both plaque and gingivitis. the aim of this study was to compare the efficacy of two concentrations of digluconate chlorhexidine (chx) solutions (0.12% and 0.20%) on gingival indices and the level of dental staining during 14 days. materials and methods: in thi...

Ethylene vinyl acetate (EVA) is in widespread use as a polymeric biomaterial with diverse applications such as intravitreal devices, catheters, artificial organs, and mouthguards. Many biomaterials are inherently prone to bacterial colonization, as the human body is host to a vast array of microbes. This can lead to infection at the biomaterial's site of implantation or application. In this stu...

chlorhexidine digluconate (CHX) on setting time, surface hardness, maximum tensile bond strength and antibacterial activity of a glass ionomer cement (GIC). The material used as control was Ketac Molar Easymix GIC. CHX was incorporated into the GIC during its manipulation at concentrations of 0.5, 1.0 and 2.0%. Antimicrobial activity against S. mutans and L. acidophilus was evaluated by means o...

UNLABELLED Chlorhexidine gluconate (CHX) is recommended for a number of clinical procedures and it has been pointed out as a potential cavity cleanser to be applied before adhesive restoration of dental cavities. OBJECTIVE As CHX may diffuse through the dentinal tubules to reach a monolayer of odontoblasts that underlies the dentin substrate, this study evaluated the cytotoxic effects of diff...