From the leaves of Phlomis aurea, two new iridoids of unique structures named 3-epiphlomurin (1) and phlomurin (2), a new megastigmane glucoside phlomuroside (3) and a new benzyl alcohol glycoside having the structure benzyl alcohol-O-beta-xylopyranosyl-(1-->2)-beta-glucopyranoside (4) have been isolated together with four known iridoids auroside, lamiide, 8-epiloganin and ipolamiide, two known...

To investigate the adipogenesis inhibitory effect on lipid accumulation, 3T3-L1 cells were treated with fractions and isolated flavonoids of Spirodela polyrhiza. An ethanol extract of S. polyrhiza was fractionated into three fractions. The butanol soluble fraction (SPB) exhibited potent antiadipogenesis activity and decreased C/EBPα and PPARγ protein expression level in 3T3-L1 cells without sig...

A new furanoisoflavone, 2'-methoxy-4',5'-methylenedioxy-[2'',3'':7,8] furanoisoflavone, leptobotryanone (1), and a new natural O-prenylated isoflavone, 4'-γ,γ-dimethylallyloxy-5,7-dihydroxyisoflavone (2), were isolated from the twigs of Millettia leptobotrya, together with twelve known flavonoids, 4'-γ,γdimethylallyloxy-5-hydroxy-7-methoxyisoflavone (3), 2',6,7-trimethoxy-4',5'-methylenedioxyis...

Chromatographic separation of an aqueous MeOH extract of Wisteria sinensis leaves has yielded six known flavonoids, two triterpene aglycones and the new acylated flavone glycoside chrysoeriol-7-O-[2''-O-(5'''-O-caffeoyl)-β-Dapiofuranosyl]-β-D-glucopyranoside (1). All metabolites were isolated for the first time from the genus Wisteria. Their structures were established on the basis of their chr...

A 35% EtOH extract of flowers of Impatiens textori MIQ. showed an inhibitory effect on blood pressure decrease in response to platelet activating factor (PAF) measured with a blood pressure monitoring system. Bioassay-guided fractionation of the 35% EtOH extract (IT) led to isolation of the flavones apigenin (1) and luteolin (3), which significantly inhibited blood pressure decrease in response...