OBJECTIVE Most physicians are unaware of the potential for complete remission from chronic musculoskeletal pain through a purely psychological approach. We report three cases in which various types of chronic musculoskeletal pain were successfully treated using a small-group psychological workshop combined with a single consultative session. DESIGN Case report. SETTING AND PATIENTS Hospital...

Muscle hyperalgesia and referred pain play an important role in chronic musculoskeletal pain. New knowledge on the involved basic mechanisms and better methods to assess muscle pain in the clinic are needed to revise and optimize treatment regimens. Increased muscle sensitivity is manifested as pain evoked by a normally non-nociceptive stimulus (allodynia), increased pain intensity evoked by no...

INTRODUCTION This protocol presents the rationale and design for a trial evaluating the efficacy of intranasal oxytocin in improving pain and function among women with chronic pelvic musculoskeletal pain. Oxytocin is a neuropeptide traditionally recognised for involvement in labour, delivery and lactation. Novel evidence suggests that oxytocin decreases pain sensitivity in humans. While oxytoci...

BACKGROUND The previous epidemiological surveys conducted in Japan revealed that once the vicious cycle of chronic musculoskeletal pain begins, it is difficult to disrupt the cycle. This finding suggests the existence of problems with the conventional approaches to treatment of chronic musculoskeletal pain. The purpose of this study was to investigate the characteristics of patients with chroni...

Introduction Multidisciplinary pain management is a useful method to treat chronic musculoskeletal pain. Few facilities in Japan administer a multidisciplinary pain management program, especially an inpatient program. Therefore, we implemented a multidisciplinary pain management program in our hospital based on biopsychosocial factors guided by the recommendations of the International Associati...

Chronic musculoskeletal pain is a complex disorder that often causes physical and psychological symptoms. While acute pain promotes healing of damaged tissue, chronic pain is caused by long-term maladaptive changes that result in hyperexcitability of pain-signaling neurons. Potassium channels have recently been implicated in pain syndromes because they largely determine the characteristics for ...

UNLABELLED There is emerging evidence that chronic musculoskeletal pain is associated with anatomic and functional abnormalities in gray matter. However, little research has investigated the relationship between chronic musculoskeletal pain and white matter. In this study, we used whole-brain tract-based spatial statistics and region-of-interest analyses of diffusion tensor imaging data to demo...