نتایج جستجو برای: chromanone
تعداد نتایج: 76 فیلتر نتایج به سال:
microwave irradiation is used in the synthesis of four tricyclic chromanones 11-14. the chromanone 14 and 12 are selectively formed thermally and under microwave in the presence of polyphosphoric acid (ppa) from the same dicarboxylic acid 9, respectively. the crystal structures of the two diacids are also reported. the corresponding ortho and meta isomers of diacids crystallize in the space gro...
In the title compound, C(21)H(20)O(3), the tolyl ring makes a dihedral angle of 31.11 (6)° with the benzene ring of the chromanone unit. The pyrone ring adopts a half-chair conformation. The mol-ecular structure is stabilized by a weak intra-molecular C-H⋯O inter-action and the crystal packing is stabilized by weak inter-molecular C-H⋯O inter-actions and a C-H⋯π inter-action.
The title compound, C(22)H(21)FO(2), exhibits substitutional disorder of the F atom and a H atom in the asymmetric unit with different occupancies, the refined F:H ratio being 0.80 (2):0.20 (2). The dihedral angle between the fluorinated benzene ring and the benzene ring of the chromanone system is 37.30°. There are two relatively high residual electron-density peaks associated with the disorder.
The distinctive feature of the structure of the title compound, C(16)H(10)Cl(2)O(2), is the formation of a zigzag chain along [100] via Cl⋯Cl inter-actions [3.591 (1) and 3.631 (1) Å]. The chroman-one moiety is fused with the benzene ring and adopts a half-chair conformation. The dihedral angle between the benzene ring of the chromanone moiety and the dichlorobenzene plane is 56.14 (8)°.
Objective(s): Chalcones and their rigid analogues represent an important class of small molecules having anticancer activities. Therefore, in this study the synthesis and cytotoxic activity of new 3-benzylidenchroman-4-ones were described as rigid chalcone analogues. Materials and Methods: The reaction of resorcinol with 3-chloropropionic acid in the presence of CF3SO3H was a...
Background and purpose: Despite growing list of antifungal agents, their clinical value has been limited by their relatively high risk of toxicity, the emergence of drug resistance, and insufficiencies in their antifungal activity. This situation has led to an ongoing search for potent broad spectrum antifungal agents with low side effects, which can be administered both orally and parenteral...
Three known flavones and seven known homoisoflavonoids were isolated from the methanolic extract of the leaves of Agave sisalanaPerrine ex Engelm. Their structures were elucidated on the basis of spectroscopic analysis. The isolated compounds were also evaluated for immunopharmacological activity. PBMC were used as target cells, and cell proliferation was determined by (3)H-thymidine uptake. (+...
ترکیبات 3-hydroxymethyldihydrobenzofuran foluenesulfonate and 10,4-hydroxymethyl-2,3-dihydrobenzopyran toluenesulfonate 19 تهیه شده اند. ترکیب تالوئن سولفات 10 از راه زیر تهیه شده است . 3-coumaranone 2 از دو روش تهیه شده است . در روش اول 2-phenoxyacetic acid 1 از فنیل و کلرواستیک اسید تهیه شده که بعد به کلرید نظیرش تبدیل گردید و این جسم بنوبه خود تحت واکنش فریدل - کرافت در اثر حلقوی شدن به جسم ...
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