background there are several studies in the literature investigating factors which can induce non-alcoholic fatty liver disease (nafld) in different populations. however, the existing literature lacks powerful studies addressing the factors which may predict the severity of nafld. objectives in the current study, we aimed to evaluate factors independently associated with liver echogenicity in a...

background non-alcoholic fatty liver disease (nafld) is a growing diagnosed condition which causes a wide spectrum of liver disorders. there is a lot of evidence introducing nafld as a risk factor for coronary artery disease (cad) but there is substantial challenge on the independency of this correlation. conclusions according to the results of the current study, the prevalence of nafld among t...

context non-alcoholic fatty liver disease (nafld) is a chronic liver disease, with 5-10% of liver having extra fat. increase in its prevalence in all age groups is linked with obesity and type ii diabetes. the treatment of nafld remains controversial. a growing body of evidence suggests a relation between overgrowth of gut microbiota with nafld and non-alcoholic steatohepatitis (nash). the obje...

background: gastrointestinal and liver diseases (gild) constitute a noteworthy portion of causes of death and disability in iran. however, data on their prevalence and burden is sparse in iran. the global burden of disease (gbd) study in 2010 has provided invaluable comprehensive data on the burden of gild in iran methods: estimations of death, years of life lost due to premature death (yll), y...

materials and methods in this case-control study, using the polymerase chain reaction (pcr), adrs266729 and rs2241766 gene polymorphisms were genotyped in b-type ultrasonography-proven nafld patients, with (n = 246) or without (n = 247) cad and in healthy controls (n = 304). serum lipid profiles were determined using biochemical methods. statistical analyses were performed using spss 17.0 stati...

conclusions pain management in patients with liver dysfunction is always challenging to physicians because of the adverse reactions of drugs, especially opioids. opioids should be used cautiously since they can cause sedation, constipation and sudden encephalopathy effects. since the clearance of these drugs in patients with hepatic insufficiency is decreased, the initial dose must be decreased...

non-alcoholic fatty liver disease (nafld) is the leading cause of chronic liver disease in the united states and other industrialized countries, and the reported prevalence in the developing countries is also rather high. this disease is associated with a high rate of morbidity and mortality and damage to the other organs. the cardiovascular system is, perhaps, the most vulnerable organ to nafl...

conclusions this intervention offers a practical approach for treatment of patients with nafld with diet therapy. patients and methods forty four patients with nafld received a diet including a 500 to 1000 kcal per day intake reduction as30% fat, 15% protein, and 55% carbohydrate for six months. anthropometric parameters, alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma g...

background: we aimed to determine the frequency of liver copper storage diseases in iranian children with cryptogenic chronic liver disease (cld). materials and methods: one-hundred and twenty children (52 girls, 70 boys; age range: 3 months-14 years) with cld who attended children's medical center in tehran, iran during the years 1997 through 1999, were enrolled. all viral, metabolic and autoi...