نتایج جستجو برای: choline oxidase

تعداد نتایج: 63616  

Choline oxidase (ChOx) was chosen as a model enzyme for evaluating the performance of CNTs’ functional groups for development of enzyme electrodes. CNTs were functionalized with carboxylic acid, amine or amide groups. Carboxylic acid, amine and amide functionalized CNTs were obtained by acid treatment, ethylenediamine or tetraethylenepentamine chemically modification and ammonia plasma treatmen...

2015
Steffan Finnegan STEFFAN FINNEGAN Giovanni Gadda

The enzymatic oxidation of choline to glycine betaine is of interest because organisms accumulate glycine betaine intracellularly in response to stress conditions, as such it is of potential interest for the genetic engineering of crops that do not naturally possess efficient pathways for the synthesis of glycine betaine, and for the potential development of drugs that target the glycine betain...

Journal: :Acta biochimica Polonica 2008
Azadeh Hekmat Ali Akbar Saboury Ali Akbar Moosavi-Movahedi Hedayatollah Ghourchian Faizan Ahmad

A reversible effect of pH on the ionization of amino-acid residues at the active center of choline oxidase was observed near the optimum pH (8). Inactivation of choline oxidase took place in the pH ranges 3-6 and 9-11, in which irreversible changes in the structure occur leading to the enzyme inactivation. The first order rate constants of the enzyme's inactivation at various pH values were est...

Journal: :Journal of Biological Chemistry 1942

Journal: :The Plant journal : for cell and molecular biology 2004
Eung-Jun Park Zoran Jeknić Atsushi Sakamoto Jeanine DeNoma Raweewan Yuwansiri Norio Murata Tony H H Chen

Tomato (Lycopersicon esculentum Mill.) plants, which normally do not accumulate glycinebetaine (GB), are susceptible to chilling stress. Exposure to temperatures below 10 degrees C causes various injuries and greatly decreases fruit set in most cultivars. We have transformed tomato (cv. Moneymaker) with a chloroplast-targeted codA gene of Arthrobacter globiformis, which encodes choline oxidase ...

Journal: :Journal of Enzyme Inhibition and Medicinal Chemistry 2006

Journal: :Chemical communications 2014
L J Friesen-Waldner C N Wiens T P Wade K Thind K P Sinclair Y Hovav J M Gomori J Sosna C A McKenzie R Katz-Brull

A specialized kinetic analysis of real-time hyperpolarized [1,1,2,2-D4, 1-(13)C]choline (13)C-magnetic resonance spectroscopy enabled the determination of initial rates of metabolic enzyme activity (choline oxidase), enzyme-substrate affinity (Km), and inhibition. In a clinical MRI scanner, metabolite levels lower than 16 μM were detected at a temporal resolution of 1 s.

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