نتایج جستجو برای: cholesterol ldl

تعداد نتایج: 98603  

Journal: :The Journal of Cell Biology 1989
L Liscum R M Ruggiero J R Faust

Niemann-Pick disease type C (NPC) is characterized by substantial intracellular accumulation of unesterified cholesterol. The accumulation of unesterified cholesterol in NPC fibroblasts cultured with low density lipoprotein (LDL) appears to result from the inability of LDL to stimulate cholesterol esterification in addition to impaired LDL-mediated downregulation of LDL receptor activity and ce...

2017
Yoshiji Yamada Jun Sakuma Ichiro Takeuchi Yoshiki Yasukochi Kimihiko Kato Mitsutoshi Oguri Tetsuo Fujimaki Hideki Horibe Masaaki Muramatsu Motoji Sawabe Yoshinori Fujiwara Yu Taniguchi Shuichi Obuchi Hisashi Kawai Shoji Shinkai Seijiro Mori Tomio Arai Masashi Tanaka

We have performed exome-wide association studies to identify single nucleotide polymorphisms that influence serum concentrations of triglycerides, high density lipoprotein (HDL)-cholesterol, or low density lipoprotein (LDL)-cholesterol or confer susceptibility to hypertriglyceridemia, hypo-HDL-cholesterolemia, or hyper-LDL-cholesterolemia in Japanese. Exome-wide association studies for serum tr...

Journal: : 2022

The present study aimed to find out the effect of Metformin drug on some biochemical parameters, including Glucose and lipid profile: Cholesterol, Triglycerides, High density lipoprotein HDL-CH, low LDL-C Male albino rats were used in this study.
 results showed that development diabetes induced by alloxan led a significant increase levels glucose, cholesterol, triglycerides, low-density c...

2005
Richard W. St. Clair Phillip Greenspan Molly Leight

Previous studies have shown that the large molecular weight low density lipoprotein (LDL) of abnormal composition isolated from hypercholesterolemic nonhuman primates stimulates greater cholesterol accumulation in cells in culture than does the same amount of normal LDL. The purpose of the present study was to determine if a correlation existed over a range of LDL molecular weights with cholest...

اعظم پناه, شیرین , عسگری, صدیقه , فتاحی, زهرا , نادری, غلامعلی ,

Background: Several studies were pointed to oxidized LDL (OX-LDL) as one of the main immunogenic agents which have important roles in primary lesions of atherosclerosis. In this study, via immunization against OX-LDL with two different antigens in an animal model (rabbit) we tried to clear relation between immune system and atherosclerosis. Methods: LDL was isolated from healthy human plasma an...

Journal: :iranian journal of basic medical sciences 0
parichehr hayatdavoudi neurogenic inflammation research center, department of physiology, faculty of medicine, mashhad university of medical sciences, mashhad, iran mohsen ghasemi faculty of medicine, north khorasan university of medical sciences, bojnurd, iran bamdad zendehbad neurogenic inflammation research center, department of physiology, faculty of medicine, mashhad university of medical sciences, mashhad, iran mohammad soukhtanloo department of medical biochemistry, faculty of medicine, mashhad university of medical sciences, mashhad, iran alireza golshan faculty of medicine, north khorasan university of medical sciences, bojnurd, iran mousa al-reza hadjzadeh neurocognitive research center, department of physiology, faculty of medicine, mashhad university of medical sciences, mashhad, iran

objective(s): leptin exerts various effects on appetite and body weight. disruption of the obesitygene is precedent to fatness. insulin or glucose elevates leptin, but streptozotocin reduces it. however, controversial data exist for the effects of leptin on diabetes and leptin level in each gender. leptin can damage the kidney function but little evidence exists for its hepatic effects. the aim...

Journal: :iranian journal of neurology 0
mansoureh togha neurology department, sina hospital, tehran university of medical sciences, tehran, iran ; iranian center of neurological research, tehran university of medical sciences, tehran, iran. mohamad reza gheini neurology department, sina hospital, tehran university of medical sciences, tehran, iran ; iranian center of neurological research, tehran university of medical sciences, tehran, iran. babak ahmadi neurology department, sina hospital, tehran university of medical sciences, tehran, iran; iranian center of neurological research,tehran university of medical sciences, tehran, iran. patricia khashaiar neurology department, sina hospital, tehran university of medical sciences, tehran, iran; iranian center of neurological research, tehran university of medical sciences, tehran, iran. soodeh razeghi neurology department, sina hospital, tehran university of medical sciences, tehran, iran; iranian center of neurological research, tehran university of medical sciences,tehran, iran.

background: changes in the lipid profile have been suggested as a risk factor for developing ischemic stroke. their role in intra-cerebral hemorrhage, however, is not clear. the present study was designed to evaluate the lipid profile levels of patients who had experienced an acute stroke during the first 24-hour and to compare these levels in different patients suffering from the stroke, eithe...

Journal: :The American journal of clinical nutrition 1994
L A Woollett J M Dietschy

The concentration of cholesterol in the low-density-lipoprotein (LDL) fraction of plasma is one of the major risk factors for coronary heart disease. Steady-state concentrations of LDL cholesterol in the plasma are determined primarily by the production rate and the rate of removal of LDL cholesterol from the circulation by receptor-dependent transport. The magnitude of these two processes is a...

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