Multiple myeloma can occasionally present with jaundice. The underlying process may be pancreatic head myeloma infiltration causing obstructive jaundice or hepatic amyloid deposition resulting in cholestatic jaundice. A rare case of myeloma presenting as jaundice due to hepatic myeloma infiltration is reported.

The occurrence of hepatitis in patients taking methyldopa was first described over 10 years ago (Gillespie et al., 1962). Though the degree of bile retention in puiblished case reports varies considerably (Tysell and Knauer, 1971) the clinical picture described is generally indistinguishable from viral hepatitis. When the following patient was seen drug-induced jaundice was suspected but as we ...

Objective: To study the value of ALT / ALP ratio (R value) for the differential diagnosis of hepatocellular jaundice and cholestatic jaundice and compare the diagnostic sensitivity of R values and the traditional D / T (DBIL / TBIL) values. Method: We randomly collected 336 cases patients with confirmed diagnosis of dominant jaundice from January 2004 to December 2006 in our hospital and record...

BACKGROUND Cholestatic jaundice as a presenting symptom of Precursor T-lymphoblastic leukemia (T-ALL)/lymphoma (T-LBL) has never been reported in literature. Similarly, precursor T-ALL/T-LBL is characteristically negative for synaptophysin. We report the first case of a patient with precursor T-ALL/T-LBL who presented with cholestatic jaundice and aberrant tumor expression of synaptophysin. C...

Hepatic involvement in primary amyloidosis (AL type) is not rare but is often clinically silent. However, presentation with jaundice in AL-type amyloidosis is rare, with an incidence of less than 5% reported in the literature. It is considered to be a preterminal sign. We herein report on a case of primary hepatic amyloidosis presenting with severe intrahepatic cholestasis. Viral, drug, alcohol...

Introduction: Hyperthyroidism is a known cause of nonspecific abnormalities in liver biochemitries; most commonly mild elevations in serum bilirubin and liver enzymes. Case Report: A case of severe cholestatic jaundice secondary to Grave’s disease. The patient is a 28­year­old African­American male who presented to the emergency room with chronic diarrhea, weight loss and jaundice. At presentat...

Therapeutic voriconazole concentrations have a narrow window of effectiveness before causing cholestatic hepatitis. After undergoing 1 year of voriconazole therapy for pulmonary aspergillosis, a 44-year-old man began treatment with 30 mg lansoprazole for gastroesophageal reflux symptoms. Within 5 days of starting treatment with lansoprazole, the patient presented with fatigue, jaundice, and cho...