To estimate the levels of folic acid, vitamin B12 and their relationship with ferritin in βthalassemia major children. Thirty children with β-thalassemia major in the age group of 4 to 8 years were studied for estimation of serum ferritin, folic acid and vitamin B12 over a period of one year. These tests were determined by means of Immulite 1000 analyzer. The statistical analysis of β-thalassem...

Background: Thalassemia is an inherited disorder of hemoglobin (Hb) synthesis. Treatment thalassemia has not yet reached the level cure. Globally, management symptomatic in form lifelong blood transfusions. Data on children with major Indonesia been widely published. However, various studies clearly showed growth and development disorders behavior that greatly affected quality life thalassemia....

The prevalaence of anemia, iron deficiency, thalassemia and glucose-6-phosphate dehydrogenase (G-6-PD) deficiency were examined among 265 hill-tribe school children, 8-14 years of age, from Omkoi District, Chiang Mai Province, Thailand. Anemia was observed in 20 school children, of whom 3 had iron deficiency anemia. The prevalence of G-6-PD deficiency and β-thalassemia trait [codon 17 (A>T), IV...

BACKGROUND Melioidosis is an important cause of community-acquired infection in Southeast Asia and northern Australia. Studies from endemic countries have demonstrated differences in the epidemiology and clinical features among children diagnosed with melioidosis. This suggests that local data are needed to determine the risk factors and outcome in specific areas. METHODS This was a retrospec...

BMI (Body Mass Index) Body Fat %, Obesity PFT (FEV1, FVC, FEV1/FVC %) Skin fold thickness WHR (Waist-Hip Ratio) BACKGROUND: Thalassemia majoris a hereditary anemia which is caused by defective synthesis of hemoglobin, ineffective erythropoiesis and rapid erythrocyte breakdown.Transfusions in beta thalassemia major are necessary for survival of these patients.Frequent blood transfusions and inad...

BACKGROUND Thalassemia Major is a preventable genetic disorder characterized by abnormal hemoglobin synthesis and lifelong blood transfusions. The children suffering from Thalassemia Major have poor quality of life. This study was conducted to assess the factors influencing quality of life of these children and how it can be improved. METHODS A descriptive cross sectional study was conducted ...

Using a mouse monoclonal antibody (mAb) (“2D4”) with high specific reactivity to Hb Bart’s and a rabbit polyclonal antibody (“RPB”) with high reactivity to Hb Bart’s but low reactivity to HbF, an ELISA assay was developed for the quantification of Hb Bart’s in hemolysates of peripheral blood. In the preliminary study, hemoglobin solutions containing 4,000 μg/mL of hemoglobin were analyzed for t...

Background: Thalassemia is a serious inherited blood disorder. Children and adolescent living with thalassemia major require lifelong repeated transfusions costly medicines for their survival. In India, β-thalassemia prevalence 3-4%. are basic pillars of society although they the most vulnerable part in view nutrition, education social life.Methods: Cross-sectional, observational study was cond...

Objective: The purpose of the study was to examine the blood lipid profile in children with beta-Thalassemia major, and to determine the factors that affect it. Material and Method: Files of eighty-five patients between the ages of five and fifteen with beta-Thalassemia major who were receiving regular chelation therapy followed by from paediatric policlinic of our hospital were examined retros...

Background: Thalassemia is a chronic disease that it leads to psychological and social problems for parents. Mothers are at markedly increased risk of suffering from psychological distress and depression because they usually take on a considerable part of extra care that their children need.This study was designed to determine prevalence and intensity of depression in mothers with a thalassemic...