Background: The Committee on Publication Ethics (COPE) and the International of Medical Journal Editors (ICMJE) are two internationally recognised organisations in field publication ethics. Guidelines from these were updated 2018. Obj ectives: To assess extent to which journal P h a r ma ctuel is compliant with guidelines ethics by ICMJE COPE 2018 and, where found  wanting, take necess...

Background: Mucocele of the appendix is a clinical term for a pseudocyst that is associated with mucus extravasation into the surrounding medium. This may be the result of neoplastic causes. Case Presentation: Two cases of the mucocele of the appendix at Golestan hospital of Ahwaz were found. The first case was a 70 years lady who complained of the pain in lower part of her abdomen since 1 yea...

This paper presents a linkage factors synthesis and multi-level optimization technique for bi-stable compliant mechanism. The linkage synthesis problem is modeled as multiple level factors and responses optimization problem with constraints. The bi-stable compliant mechanism is modeled as a crank slider mechanism using pseudo-rigid-body model (PRBM). The model exerts the large deflection of fle...

"Music on hold" is one of the features of telephone systems that is most desired by buyers of business telephone systems. Music on hold means that when one party to a call has the call "on hold", that party’s telephone provides an audio stream (often music) to be heard by the other party. Architectural features of SIP make it difficult to implement music on hold in a way that is fully standards...

Computer technology has the potential to significantly reduce the risks associated with scenery motion in live theatre, as well as enhancing the spectacle of performance. The industry is becoming more concerned about safety standards compliance. IEC 61508 is emerging as the universally favoured standard for functional safety of stage machinery control systems.

Background: Both primary and secondary tumors can develop in distal phalanx of the hand presenting as lytic lesions. The presence of a lytic lesion in the distal phalanx has been a dilemma making the differential diagnoses, prognosis, and treatment of these lesions challenging. Objectives: This study was designed to evaluate the patients who were presented with a lytic lesion in their distal ph...

in this study, our aim was to produce a generation of gmp-grade adipose tissue-derived mesenchymal stem cells for clinical applications. according to our results, we fulfill to establish consistent and also reproducible current good manufacturing practice (cgmp) compliant adipose tissue-derived mesenchymal stem cells from five female donors. the isolated cells were cultured in dmem supplemented...

Papillion-Lefèvre Syndrome is a very rare disorder of autosomal recessive inheritance distinguished by palmar plantar hyperkeratosis and early onset of periodontitis affecting the dentition. Genetic studies have identified a mutation in the major gene locus of chromosome 11q14 with loss of function. Cathepsin C gene is to be responsible for Papillion-Lefèvre Syndrome. The present case report de...