BACKGROUND Addition of intrathecal magnesium sulfate to local anesthetics has been reported to potentiate spinal anesthesia and prolong analgesia in parturients. The current study was to determine whether intrathecal magnesium sulfate would reduce the dose of hyperbaric bupivacaine in spinal anesthesia with bupivacaine and sufentanil for cesarean delivery. METHODS Sixty healthy parturients un...

INTRODUCTION Non-communicable diseases (NCD) now represent the major burden of adverse health in most countries. It is clear that much of the risk of such conditions begins very early in life, potentially in utero. Given their complex aetiology, an understanding of the origins of NCD requires an in-depth analysis of the interplay between genetic variation and environment, preferably over time. ...

BACKGROUND Chinese herbal medicine (CHM) has been used in China and some other countries for the treatment of patients with functional dyspepsia (FD). However, controlled studies supporting the efficacy of such treatments in patients with FD are lacking. In this trial, we aimed to assess the efficacy and safety of modified LiuJunZi decoction in patients with FD of spleen-deficiency and qi-stagn...

BACKGROUND It has been known that Dexmedetomidine pre-medication enhances the effects of volatile anesthetics, reduces the need of sevoflurane, and facilitates smooth extubation in anesthetized children. This present study was designed to determine the effects of different doses of intravenous dexmedetomidine pre-medication on minimum alveolar concentration of sevoflurane for smooth tracheal ex...

BACKGROUND Although pre-emptive analgesia is commonly used for the management of postoperative pain in developed countries, no defined protocol has been carried out and widely practiced, especially in transabdominal hysterectomy. Keeping this in mind the present study aimed to investigate the effects of multimodal pre-emptive analgesia on pain management, stress response and inflammatory factor...

BACKGROUND Hypertension affects one billion people globally and is one of the leading risk factors for cardiovascular and renal diseases. However, hypertension management remains poor, especially in rural China. METHODS A clustered randomized controlled trial was conducted in six towns in China's Qianjiang county between 7/2012 and 6/2014, including 5462 hypertension patients above 35 years o...

Abstract Background Acute renal colic caused by urinary calculi (ARCUC) has a considerable impact on the quality of life. Acupuncture might be potential treatment option. However, evidence is limited. We will conduct this trial to evaluate efficacy and safety acupuncture as adjunctive diclofenac for ARCUC. Methods/design A total 80 eligible patients who are diagnosed with stone randomly allocat...

Glucocorticoids (GC) are used as the first-line treatment of immune thrombocytopenia (ITP), but 10-20% patients insensitive to them. Regulatory T cells (Tregs) can maintain tolerance in autoimmune diseases. The present research pooled 55 with newly diagnosed ITP and 44 healthy volunteers from seven hospitals. All received GC were divided into GC-sensitive GC-insensitive groups according curativ...

Traditional Chinese medicine (TCM) is a valuable form of with long history in China. It has played significant role the control and prevention infectious diseases including SARS H7N9 flu. After outbreak COVID-19, China's National Health Commission included TCM Diagnosis Treatment Protocol for COVID-19. During COVID-19 pandemic, three traditional medicines (Jinhua Qinggan granules, Lianhua Qingw...

BACKGROUND Evidence from quantitative studies suggest that Tai Chi produces a variety of health-related benefits, but few qualitative studies have investigated how older adults perceive the benefit of Tai Chi. The objective of the current study was to qualitatively evaluate the perceived benefits of Tai Chi practice among community older population. METHODS This study was conducted with parti...