Published by Kowsar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The globally increasing incidence of cancer and its associated mortality has become a main challenge for humankind. This problem is more serious in ...

Here we present the case of a patient with diffuse large B-cell lymphoma who was admitted to hospital for an elective autologous peripheral blood stem cell transplant after cytotoxic treatment with lomustine, cytarabine, cyclophosphomide and etoposide (LACE). On the final day of chemotherapeutic treatment, she developed sudden onset dyspnoea. Electrocardiography confirmed acute antero-lateral T...

The optimal management of cancer in patients with severe heart failure is not defined. This issue is particularly challenging when a diagnosis of limited-stage small cell lung cancer (SCLC) is made incidentally in the context of evaluating patient for candidacy for cardiac transplantation. Limited-stage SCLC is typically managed on a curative therapeutic paradigm with combined modality approach...

conclusions the mechanism of mid-variant of dobutamine-induced stress cardiomyopathy remains unclear. we think that multiple mechanisms are involved and this risk should be considered in patients with comorbid psychiatric conditions and with use of centrally acting stimulants. case presentation we report a 48-year-old female with intermittent chest pain. her physical exam, cardiac enzymes and t...

Case Study: H.M. is a 70-year-old woman with a known history of metastatic breast cancer. In 1995, she underwent a right modifi ed radical mastectomy followed by four years of hormonal therapy with tamoxifen. In April 2001, she was diagnosed with bone metastases and placed on letrozole, zoledronic acid, and chemotherapy consisting of gemcitabine and docetaxel. She experienced severe mucositis, ...

Cardiotoxicity is a well known adverse effect of chemotherapy. Multiple cardiac injuries have been reported including cardiomyopathy, pericarditis, myocarditis, angina, arrhythmias, and myocardial infarction. A left ventricular aneurysm due to chemotherapy is a rare and a dangerous complication which is particularly challenging in diagnosis requiring a high index of suspicion and periodic imagi...

Introduction: The objective of this study is to determine the major causes of early death in acute lymphoblastic leukemia (ALL).  Methods: The following databases including PubMed, EMBASE, Science Direct and Google Scholar were searched for following terms: “acute lymphoblastic leukemia”, “early mortality”, “early death “ and “death in induction phase “. Inclusion criteria were all studies abo...